2020-01-01から1年間の記事一覧

リパーゼ

Hormone-sensitive lipase https://www.uniprot.org/uniprot/Q05469 EC:3.1.1.79 Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters…

アシルCoAデヒドロゲナーゼ

Short-chain specific acyl-CoA dehydrogenase, mitochondrial https://www.uniprot.org/uniprot/P16219 EC:1.3.8.1 Butyryl-CoA dehydrogenase Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the firs…

proteases

kallikrein-1 Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykini…

Protein PML

https://www.uniprot.org/uniprot/P29590 Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA dam…

Pro-thyrotropin-releasing hormone

https://www.uniprot.org/uniprot/P20396 As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as m…

leptin

https://www.uniprot.org/uniprot/P41159Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in t…

adiponectin

- https://www.uniprot.org/uniprot/Q15848 Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation a…

Gi

Alpha-2A adrenergic receptor Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonid…

Vasodilator-stimulated phosphoprotein

https://www.uniprot.org/uniprot/P50552 Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, pl…

ミトコンドリア局在のシグナル配列

CS MALLTAAARL LGTKNASCLV LAARHAS PDH MRKMLAAVSR VLSGASQKPA SRVLVASRN Fumarate hydratase MYRALRLLAR SRPLVRAPAA ALASAPGLGG AAVPSFWPPN AARM Long-chain specific acyl-CoA dehydrogenase MAARLLRGSL RVLGGHRAPR QLPAARCSHS Pyruvate carboxylase MLKFR…

Proteinase-activated receptor 1

https://www.uniprot.org/uniprot/P25116 活性化されたトロンビンと高い親和性で結合し、Gq経由でホスホイノシチドを加水分解する。血小板の活性化と血管の発達に働く。 High affinity receptor for activated thrombin coupled to G proteins that stimulat…

EC 6. Ligases

https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC6/cont6a.html EC 6.1 Forming Carbon-Oxygen Bonds EC 6.1.1 Ligases Forming Aminoacyl-tRNA and Related Compounds EC 6.1.1.1 tyrosine—tRNA ligase EC 6.1.1.2 tryptophan—tRNA ligase EC 6.1.1.3 threonin…

EC 5. Isomerases

https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC5/cont5a.html EC 5.1 Racemases and Epimerases EC 5.1.1 Acting on Amino Acids and Derivatives EC 5.1.1.1 alanine racemase EC 5.1.1.2 methionine racemase EC 5.1.1.3 glutamate racemase EC 5.1.1.4 pro…

EC 4 Lyases

https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC4/cont4a.html EC 4.1 Carbon-Carbon Lyases EC 4.1.1 Carboxy-Lyases EC 4.1.1.1 pyruvate decarboxylase EC 4.1.1.2 oxalate decarboxylase EC 4.1.1.3 now EC 7.2.4.2 and EC 4.1.1.112 EC 4.1.1.4 acetoacet…

EC 3. Hydrolases

https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC3/cont3aa.html https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC3/cont3bb.htmlEC3群(加水分解酵素、ヒドロラーゼ) 小群1(EC3.1):エステル結合の加水分解 (EC3.1.1.x):カルボン酸エステルの加水分解 (EC3…

EC 2. Transferases

https://www.qmul.ac.uk/sbcs/iubmb/enzyme/ EC 2.1 Transferring One-Carbon Groups EC 2.1.1 Methyltransferases EC 2.1.1.1 nicotinamide N-methyltransferase EC 2.1.1.2 guanidinoacetate N-methyltransferase EC 2.1.1.3 thetin—homocysteine S-methyl…

EC 1 Oxidoreductases

EC 1.1 Acting on the CH-OH group of donors(小群1:アルコール性水酸基が電子を放出) EC 1.1.1 With NAD+ or NADP+ as acceptor(組1:NAD+またはNADP+が電子を受容) EC 1.1.1.1 alcohol dehydrogenase EC 1.1.1.2 alcohol dehydrogenase (NADP+) EC …

EC 7. Translocases

EC 7.1 Catalysing the translocation of hydrons(水素イオンを移動させる) EC 7.1.1 Hydron translocation or charge separation linked to oxidoreductase reactions(酸化還元反応を伴う) EC 7.1.1.1 proton-translocating NAD(P)+ transhydrogenase E…

講義が始まる

ようやく、来週月曜日(4月20日)から講義が始まります。 ムードルも今まで全く使っていなかったので、急遽用意しました。 もし、アクセスが混んでいてうまく繋がらない時のために、こちら側にも講義資料等へのリンクをしておきます。 (練習問題の方は、Moo…