2024-01-01から1年間の記事一覧

BNP

https://www.uniprot.org/uniprotkb/P16860/entryBrain natriuretic peptide 32 Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed:9458824, PubMed:1672777, PubMed:1914098, PubMed:17372040). May also function as …

Conversion of Brain natriuretic peptide

Neprilysin https://www.uniprot.org/uniprotkb/P08473/entry Function Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:6349683, PubMed:6208535, PubMed:15283675, PubMed:8168535). Bi…

Mast/stem cell growth factor receptor Kit

https://www.uniprot.org/uniprotkb/P10721/entry Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem ce…

Proto-oncogene tyrosine-protein kinase receptor Ret

https://www.uniprot.org/uniprotkb/P07949/entry Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial ce…

FLT-3 (Fms-like tyrosine kinase 3)

https://www.uniprot.org/uniprotkb/P36888/entry Stem cell tyrosine kinase 1 CD135Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic…

ブルトン型チロシンキナーゼ Tyrosine-protein kinase BTK

https://www.uniprot.org/uniprotkb/Q06187/entry Function Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling (PubMed:19290921). Binding of antigen to the B-cell antigen receptor (BCR) trigg…

Receptor-type tyrosine-protein kinase FLT3

https://www.uniprot.org/uniprotkb/P36888/entry FL cytokine receptor Fetal liver kinase-2 (FLK-2) Fms-like tyrosine kinase 3 (FLT-3) Stem cell tyrosine kinase 1 (STK-1) CD Antigen Name CD135 Function function Tyrosine-protein kinase that ac…

ALK tyrosine kinase receptor

https://www.uniprot.org/uniprotkb/Q9UM73/entry Function Neuronal receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an important role in the ge…

MAPK

ERK1 Extracellular signal-regulated kinase 1 (ERK-1) https://www.uniprot.org/uniprotkb/P27361/entry セリントレオニンキナーゼ MAPK1/ERK2とMAPK3/ERK1がMAPKカスケードで重要な役割を果たす。 転写因子(ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1)…

がん原遺伝子

ALK https://www.uniprot.org/uniprotkb/Q9UM73/entry ROS1 https://www.uniprot.org/uniprotkb/P08922/entry NTRK1 - https://www.uniprot.org/uniprotkb/P04629/entry JUN https://www.uniprot.org/uniprotkb/P05412/entry 核内に局在する転写因子。AP-1の…