Glucagon 180アミノ酸よりなる前駆体がPCSK1、またはPCSK2（神経内分泌変換酵素）により切断され、グルカゴン（53-81、26ペプチド）やglucagon-like peptide 1(GLP-1)（92 – 128アミノ酸、37ペプチドの前駆体）などを生じる。 Cleaved into the following 8 …

methimazole Description A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation…

DESCRIPTION A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Ex…

EC=1.14.13.159 Alternative name(s): Cytochrome P450 2R1 Function Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D2 and D3. Ref.1 Ref.2 Ref.5 Catalytic activity Calciol + O2 + NADPH = calcidiol + NADP+ H2O. Ref.1 Ref.2 …

Lactoperoxidase Short name=LPO EC=1.11.1.7 Alternative name(s): Salivary peroxidase Short name=SPO :Function May contribute to airway host defense against infection. Ref.7 Catalytic activity 2 phenolic donor + H2O2 = 2 phenoxyl radical of …

Short name=TPO EC=1.11.1.8 Gene names Name: TPO Organism Homo sapiens (Human) [Reference proteome] Protein attributesSequence length 933 AA. Sequence status Complete. Sequence processing The displayed sequence is further processed into a m…

Function Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Subunit structure Homodimer. Subcellular location Secreted. Tissue specificity Thyroid gland specific. Post-translational modification Sulfated …