2019-10-01から1ヶ月間の記事一覧

LCAT

Phosphatidylcholine-sterol acyltransferase Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) t…

von Willebrand factor

https://www.uniprot.org/uniprot/P04275 止血の制御に重要。血管内皮下のコラーゲンと血小板表面の受容体複合体(GP1b-IX-V)との間に架橋し血小板が血管の損傷部位に粘着するのをうながす。 血液凝固第8因子のシャペロンとして働く。 Important in the mai…

Vitamin K-dependent protein S

https://www.uniprot.org/uniprot/P07225 Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.

thrombomodulin

https://www.uniprot.org/uniprot/P07204 Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (pr…

第XII因子

https://www.uniprot.org/uniprot/P00748 Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to f…