EC 3. Hydrolases

https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC3/cont3aa.html
https://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC3/cont3bb.html

EC3群(加水分解酵素、ヒドロラーゼ)

  • 小群2(EC3.2):グリコシド結合の加水分解
  • 小群3(EC3.3):エステル結合の加水分解
  • 小群4(EC3.4):ペプチド結合の加水分解
    • (EC3.4.11.x):アミノペプチダーゼ
    • (EC3.4.13.x):ジペプチダーゼ
    • (EC3.4.14.x):ジペプチジル、トリペプチジルペプチダーゼ
    • (EC3.4.15.x):アミノペプチダーゼ
    • (EC3.4.16.x):セリンペプチダーゼ
    • (EC3.4.17.x):めたろカルボキシペプチダーゼ
    • (EC3.4.15.x):アミノペプチダーゼ
  • 小群5(EC3.5):ペプチド結合以外の炭素ー窒素結合の加水分解
  • 小群6(EC3.6):酸無水物の分解
  • 小群7(EC3.7):炭素間結合の分解

EC 3.1 Acting on Ester Bonds

EC 3.1.1 Carboxylic Ester Hydrolases

EC 3.1.1.1 carboxylesterase
EC 3.1.1.2 arylesterase
EC 3.1.1.3 triacylglycerol lipase
EC 3.1.1.4 phospholipase A2
EC 3.1.1.5 lysophospholipase
EC 3.1.1.6 acetylesterase
EC 3.1.1.7 acetylcholinesterase
EC 3.1.1.8 cholinesterase
EC 3.1.1.9 deleted
EC 3.1.1.10 tropinesterase
EC 3.1.1.11 pectinesterase
EC 3.1.1.12 deleted
EC 3.1.1.13 sterol esterase
EC 3.1.1.14 chlorophyllase
EC 3.1.1.15 L-arabinonolactonase
EC 3.1.1.16 deleted, mixture of EC 5.3.3.4 and EC 3.1.1.24
EC 3.1.1.17 gluconolactonase
EC 3.1.1.18 deleted, included in EC 3.1.1.17
EC 3.1.1.19 uronolactonase
EC 3.1.1.20 tannase
EC 3.1.1.21 deleted, catalysed by EC 3.1.1.1 and EC 3.1.1.3
EC 3.1.1.22 hydroxybutyrate-dimer hydrolase
EC 3.1.1.23 acylglycerol lipase
EC 3.1.1.24 3-oxoadipate enol-lactonase
EC 3.1.1.25 1,4-lactonase
EC 3.1.1.26 galactolipase
EC 3.1.1.27 4-pyridoxolactonase
EC 3.1.1.28 acylcarnitine hydrolase
EC 3.1.1.29 aminoacyl-tRNA hydrolase
EC 3.1.1.30 D-arabinonolactonase
EC 3.1.1.31 6-phosphogluconolactonase
EC 3.1.1.32 phospholipase A1
EC 3.1.1.33 6-acetylglucose deacetylase
EC 3.1.1.34 lipoprotein lipase
EC 3.1.1.35 dihydrocoumarin hydrolase
EC 3.1.1.36 limonin-D-ring-lactonase
EC 3.1.1.37 steroid-lactonase
EC 3.1.1.38 triacetate-lactonase
EC 3.1.1.39 actinomycin lactonase
EC 3.1.1.40 orsellinate-depside hydrolase
EC 3.1.1.41 cephalosporin-C deacetylase
EC 3.1.1.42 chlorogenate hydrolase
EC 3.1.1.43 α-amino-acid esterase
EC 3.1.1.44 4-methyloxaloacetate esterase
EC 3.1.1.45 carboxymethylenebutenolidase
EC 3.1.1.46 deoxylimonate A-ring-lactonase
EC 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase
EC 3.1.1.48 fusarinine-C ornithinesterase
EC 3.1.1.49 sinapine esterase
EC 3.1.1.50 wax-ester hydrolase
EC 3.1.1.51 phorbol-diester hydrolase
EC 3.1.1.52 phosphatidylinositol deacylase
EC 3.1.1.53 sialate O-acetylesterase
EC 3.1.1.54 acetoxybutynylbithiophene deacetylase
EC 3.1.1.55 acetylsalicylate deacetylase
EC 3.1.1.56 methylumbelliferyl-acetate deacetylase
EC 3.1.1.57 2-pyrone-4,6-dicarboxylate lactonase
EC 3.1.1.58 N-acetylgalactosaminoglycan deacetylase
EC 3.1.1.59 juvenile-hormone esterase
EC 3.1.1.60 bis(2-ethylhexyl)phthalate esterase
EC 3.1.1.61 protein-glutamate methylesterase
EC 3.1.1.62 now EC 3.5.1.47
EC 3.1.1.63 11-cis-retinyl-palmitate hydrolase
EC 3.1.1.64 retinoid isomerohydrolase
EC 3.1.1.65 L-rhamnono-1,4-lactonase
EC 3.1.1.66 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
EC 3.1.1.67 fatty-acyl-ethyl-ester synthase
EC 3.1.1.68 xylono-1,4-lactonase
EC 3.1.1.69 now EC 3.5.1.89
EC 3.1.1.70 cetraxate benzylesterase
EC 3.1.1.71 acetylalkylglycerol acetylhydrolase
EC 3.1.1.72 acetylxylan esterase
EC 3.1.1.73 feruloyl esterase
EC 3.1.1.74 cutinase
EC 3.1.1.75 poly(3-hydroxybutyrate) depolymerase
EC 3.1.1.76 poly(3-hydroxyoctanoate) depolymerase
EC 3.1.1.77 acyloxyacyl hydrolase
EC 3.1.1.78 polyneuridine-aldehyde esterase
EC 3.1.1.79 hormone-sensitive lipase
EC 3.1.1.80 acetylajmaline esterase
EC 3.1.1.81 quorum-quenching N-acyl-homoserine lactonase
EC 3.1.1.82 pheophorbidase
EC 3.1.1.83 monoterpene ε-lactone hydrolase
EC 3.1.1.84 cocaine esterase
EC 3.1.1.85 pimelyl-[acyl-carrier protein] methyl ester esterase
EC 3.1.1.86 rhamnogalacturonan acetylesterase
EC 3.1.1.87 fumonisin B1 esterase
EC 3.1.1.88 pyrethroid hydrolase
EC 3.1.1.89 protein phosphatase methylesterase-1
EC 3.1.1.90 all-trans-retinyl ester 13-cis isomerohydrolase
EC 3.1.1.91 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase
EC 3.1.1.92 4-sulfomuconolactone hydrolase
EC 3.1.1.93 mycophenolic acid acyl-glucuronide esterase
EC 3.1.1.94 versiconal hemiacetal acetate esterase
EC 3.1.1.95 aclacinomycin methylesterase
EC 3.1.1.96 D-aminoacyl-tRNA deacylase
EC 3.1.1.97 methylated diphthine methylhydrolase
EC 3.1.1.98 [Wnt protein] O-palmitoleoyl-L-serine hydrolase
EC 3.1.1.99 6-deoxy-6-sulfogluconolactonase
EC 3.1.1.100 chlorophyllide a hydrolase
EC 3.1.1.101 poly(ethylene terephthalate) hydrolase
EC 3.1.1.102 mono(ethylene terephthalate) hydrolase
EC 3.1.1.103 teichoic acid D-alanine hydrolase
EC 3.1.1.104 5-phospho-D-xylono-1,4-lactonase
EC 3.1.1.105 3-O-acetylpapaveroxine carboxylesterase
EC 3.1.1.106 O-acetyl-ADP-ribose deacetylase
EC 3.1.1.107 apo-salmochelin esterase
EC 3.1.1.108 ferric enterobactin esterase
EC 3.1.1.109 ferric salmochelin esterase
EC 3.1.1.110 xylono-1,5-lactonase
EC 3.1.1.111 phosphatidylserine sn-1 acylhydrolase
EC 3.1.1.112 isoamyl acetate esterase
EC 3.1.1.113 ethyl acetate hydrolase
EC 3.1.1.114 methyl acetate hydrolase

EC 3.1.2 Thioester Hydrolases

EC 3.1.2.1 acetyl-CoA hydrolase
EC 3.1.2.2 palmitoyl-CoA hydrolase
EC 3.1.2.3 succinyl-CoA hydrolase
EC 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase
EC 3.1.2.5 hydroxymethylglutaryl-CoA hydrolase
EC 3.1.2.6 hydroxyacylglutathione hydrolase
EC 3.1.2.7 glutathione thiolesterase
EC 3.1.2.8 deleted, included in EC 3.1.2.6
EC 3.1.2.9 deleted
EC 3.1.2.10 formyl-CoA hydrolase
EC 3.1.2.11 acetoacetyl-CoA hydrolase
EC 3.1.2.12 S-formylglutathione hydrolase
EC 3.1.2.13 S-succinylglutathione hydrolase
EC 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase
EC 3.1.2.15 deleted
EC 3.1.2.16 citrate lyase deacetylase
EC 3.1.2.17 (S)-methylmalonyl-CoA hydrolase
EC 3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase
EC 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase
EC 3.1.2.20 acyl-CoA hydrolase
EC 3.1.2.21 dodecanoyl-[acyl-carrier protein] hydrolase
EC 3.1.2.22 palmitoyl[protein] hydrolase
EC 3.1.2.23 4-hydroxybenzoyl-CoA thioesterase
EC 3.1.2.24 transferred entry now EC 3.13.1.3
EC 3.1.2.25 phenylacetyl-CoA hydrolase
EC 3.1.2.26 transferred now EC 2.8.3.25
EC 3.1.2.27 choloyl-CoA hydrolase
EC 3.1.2.28 1,4-dihydroxy-2-naphthoyl-CoA hydrolase
EC 3.1.2.29 fluoroacetyl-CoA thioesterase
EC 3.1.2.30 (3S)-malyl-CoA thioesterase
EC 3.1.2.31 dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase
EC 3.1.2.32 2-aminobenzoylacetyl-CoA thioesterase

EC 3.1.3 Phosphoric Monoester Hydrolases

EC 3.1.3.1 alkaline phosphatase
EC 3.1.3.2 acid phosphatase
EC 3.1.3.3 phosphoserine phosphatase
EC 3.1.3.4 phosphatidate phosphatase
EC 3.1.3.5 5'-nucleotidase
EC 3.1.3.6 3'-nucleotidase
EC 3.1.3.7 3'(2'),5'-bisphosphate nucleotidase
EC 3.1.3.8 3-phytase
EC 3.1.3.9 glucose-6-phosphatase
EC 3.1.3.10 glucose-1-phosphatase
EC 3.1.3.11 fructose-bisphosphatase
EC 3.1.3.12 trehalose-phosphatase
EC 3.1.3.13 deleted now covered by EC 5.4.2.11
EC 3.1.3.14 methylphosphothioglycerate phosphatase
EC 3.1.3.15 histidinol-phosphatase
EC 3.1.3.16 protein-serine/threonine phosphatase
EC 3.1.3.17 [phosphorylase] phosphatase
EC 3.1.3.18 phosphoglycolate phosphatase
EC 3.1.3.19 glycerol-2-phosphatase
EC 3.1.3.20 phosphoglycerate phosphatase
EC 3.1.3.21 glycerol-1-phosphatase
EC 3.1.3.22 mannitol-1-phosphatase
EC 3.1.3.23 sugar-phosphatase
EC 3.1.3.24 sucrose-phosphate phosphatase
EC 3.1.3.25 inositol-phosphate phosphatase
EC 3.1.3.26 4-phytase
EC 3.1.3.27 phosphatidylglycerophosphatase
EC 3.1.3.28 ADPphosphoglycerate phosphatase
EC 3.1.3.29 N-acylneuraminate-9-phosphatase
EC 3.1.3.30 deleted, included in EC 3.1.3.31
EC 3.1.3.31 nucleotidase
EC 3.1.3.32 polynucleotide 3'-phosphatase
EC 3.1.3.33 polynucleotide 5'-phosphatase
EC 3.1.3.34 deoxynucleotide 3'-phosphatase
EC 3.1.3.35 thymidylate 5'-phosphatase
EC 3.1.3.36 phosphoinositide 5-phosphatase
EC 3.1.3.37 sedoheptulose-bisphosphatase
EC 3.1.3.38 3-phosphoglycerate phosphatase
EC 3.1.3.39 streptomycin-6-phosphatase
EC 3.1.3.40 guanidinodeoxy-scyllo-inositol-4-phosphatase
EC 3.1.3.41 4-nitrophenylphosphatase
EC 3.1.3.42 [glycogen-synthase-D] phosphatase
EC 3.1.3.43 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase
EC 3.1.3.44 [acetyl-CoA carboxylase]-phosphatase
EC 3.1.3.45 3-deoxy-manno-octulosonate-8-phosphatase
EC 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase
EC 3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase
EC 3.1.3.48 protein-tyrosine-phosphatase
EC 3.1.3.49 [pyruvate kinase]-phosphatase
EC 3.1.3.50 sorbitol-6-phosphatase
EC 3.1.3.51 dolichyl-phosphatase
EC 3.1.3.52 [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase
EC 3.1.3.53 [myosin-light-chain] phosphatase
EC 3.1.3.54 fructose-2,6-bisphosphate 6-phosphatase
EC 3.1.3.55 caldesmon-phosphatase
EC 3.1.3.56 inositol-polyphosphate 5-phosphatase
EC 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase
EC 3.1.3.58 sugar-terminal-phosphatase
EC 3.1.3.59 alkylacetylglycerophosphatase
EC 3.1.3.60 phosphoenolpyruvate phosphatase
EC 3.1.3.61 deleted
EC 3.1.3.62 multiple inositol-polyphosphate phosphatase
EC 3.1.3.63 2-carboxy-D-arabinitol-1-phosphatase
EC 3.1.3.64 phosphatidylinositol-3-phosphatase
EC 3.1.3.65 now with EC 3.1.3.64
EC 3.1.3.66 phosphatidylinositol-3,4-bisphosphate 4-phosphatase
EC 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
EC 3.1.3.68 2-deoxyglucose-6-phosphatase
EC 3.1.3.69 glucosylglycerol 3-phosphatase
EC 3.1.3.70 mannosyl-3-phosphoglycerate phosphatase
EC 3.1.3.71 2-phosphosulfolactate phosphatase
EC 3.1.3.72 5-phytase
EC 3.1.3.73 adenosylcobalamin/α-ribazole phosphatase
EC 3.1.3.74 pyridoxal phosphatase
EC 3.1.3.75 phosphoethanolamine/phosphocholine phosphatase
EC 3.1.3.76 lipid-phosphate phosphatase
EC 3.1.3.77 acireductone synthase
EC 3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase
EC 3.1.3.79 mannosylfructose-phosphate phosphatase
EC 3.1.3.80 2,3-bisphosphoglycerate 3-phosphatase
EC 3.1.3.81 diacylglycerol diphosphate phosphatase
EC 3.1.3.82 D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase
EC 3.1.3.83 D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphatase
EC 3.1.3.84 ADP-ribose 1"-phosphate phosphatase
EC 3.1.3.85 glucosyl-3-phosphoglycerate phosphatase
EC 3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
EC 3.1.3.87 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
EC 3.1.3.88 5"-phosphoribostamycin phosphatase
EC 3.1.3.89 5'-deoxynucleotidase
EC 3.1.3.90 maltose 6'-phosphate phosphatase
EC 3.1.3.91 7-methylguanosine nucleotidase
EC 3.1.3.92 kanosamine-6-phosphate phosphatase
EC 3.1.3.93 L-galactose 1-phosphate phosphatase
EC 3.1.3.94 D-galactose 1-phosphate phosphatase
EC 3.1.3.95 phosphatidylinositol-3,5-bisphosphate 3-phosphatase
EC 3.1.3.96 pseudouridine 5'-phosphatase
EC 3.1.3.97 3',5'-nucleoside bisphosphate phosphatase
EC 3.1.3.98 now EC 3.6.1.68
EC 3.1.3.99 IMP-specific 5'-nucleotidase
EC 3.1.3.100 thiamine phosphate phosphatase
EC 3.1.3.101 validoxylamine A 7'-phosphate phosphatase
EC 3.1.3.102 FMN hydrolase
EC 3.1.3.103 3-deoxy-D-glycero-D-galacto-nononate 9-phosphatase
EC 3.1.3.104 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase
EC 3.1.3.105 N-acetyl-D-muramate 6-phosphate phosphatase
EC 3.1.3.106 2-lysophosphatidate phosphatase
EC 3.1.3.107 amicoumacin phosphatase
EC 3.1.3.108 nocturnin

EC 3.1.4 Phosphoric Diester Hydrolases

EC 3.1.4.1 phosphodiesterase I
EC 3.1.4.2 glycerophosphocholine phosphodiesterase
EC 3.1.4.3 phospholipase C
EC 3.1.4.4 phospholipase D
EC 3.1.4.5 now EC 3.1.21.1
EC 3.1.4.6 now EC 3.1.22.1
EC 3.1.4.7 now EC 3.1.31.1
EC 3.1.4.8 now EC 3.1.27.3
EC 3.1.4.9 now EC 3.1.30.2
EC 3.1.4.10 now EC 4.6.1.13
EC 3.1.4.11 phosphoinositide phospholipase C
EC 3.1.4.12 sphingomyelin phosphodiesterase
EC 3.1.4.13 serine-ethanolaminephosphate phosphodiesterase
EC 3.1.4.14 [acyl-carrier-protein] phosphodiesterase
EC 3.1.4.15 transferred, now EC 2.7.7.89
EC 3.1.4.16 2',3'-cyclic-nucleotide 2'-phosphodiesterase
EC 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
EC 3.1.4.18 now EC 3.1.16.1
EC 3.1.4.19 now EC 3.1.13.3
EC 3.1.4.20 now EC 3.1.13.1
EC 3.1.4.21 now EC 3.1.30.1
EC 3.1.4.22 now EC 3.1.27.5
EC 3.1.4.23 now EC 3.1.27.1
EC 3.1.4.24 deleted
EC 3.1.4.25 now EC 3.1.11.1
EC 3.1.4.26 deleted
EC 3.1.4.27 now EC 3.1.11.2
EC 3.1.4.28 now EC 3.1.11.3
EC 3.1.4.29 deleted
EC 3.1.4.30 now EC 3.1.21.2
EC 3.1.4.31 now EC 3.1.11.4
EC 3.1.4.32 deleted
EC 3.1.4.33 deleted
EC 3.1.4.34 deleted
EC 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
EC 3.1.4.36 now with EC 3.1.4.43
EC 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase
EC 3.1.4.38 glycerophosphocholine cholinephosphodiesterase
EC 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase
EC 3.1.4.40 CMP-N-acylneuraminate phosphodiesterase
EC 3.1.4.41 sphingomyelin phosphodiesterase D
EC 3.1.4.42 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
EC 3.1.4.43 glycerophosphoinositol inositolphosphodiesterase
EC 3.1.4.44 glycerophosphoinositol glycerophosphodiesterase
EC 3.1.4.45 N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase
EC 3.1.4.46 glycerophosphodiester phosphodiesterase
EC 3.1.4.47 now EC 4.6.1.14
EC 3.1.4.48 dolichylphosphate-glucose phosphodiesterase
EC 3.1.4.49 dolichylphosphate-mannose phosphodiesterase
EC 3.1.4.50 glycosylphosphatidylinositol phospholipase D
EC 3.1.4.51 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase
EC 3.1.4.52 cyclic-guanylate-specific phosphodiesterase
EC 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
EC 3.1.4.54 N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
EC 3.1.4.55 phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
EC 3.1.4.56 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase
EC 3.1.4.57 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase
EC 3.1.4.58 RNA 2',3'-cyclic 3'-phosphodiesterase
EC 3.1.4.59 cyclic-di-AMP phosphodiesterase
EC 3.1.4.60 pApA phosphodiesterase

EC 3.1.5 Triphosphoric Monoester Hydrolases

EC 3.1.5.1 dGTPase

EC 3.1.6 Sulfuric Ester Hydrolases

EC 3.1.6.1 arylsulfatase
EC 3.1.6.2 steryl-sulfatase
EC 3.1.6.3 glycosulfatase
EC 3.1.6.4 N-acetylgalactosamine-6-sulfatase
EC 3.1.6.5 deleted
EC 3.1.6.6 choline-sulfatase
EC 3.1.6.7 cellulose-polysulfatase
EC 3.1.6.8 cerebroside-sulfatase
EC 3.1.6.9 chondro-4-sulfatase
EC 3.1.6.10 chondro-6-sulfatase
EC 3.1.6.11 disulfoglucosamine-6-sulfatase
EC 3.1.6.12 N-acetylgalactosamine-4-sulfatase
EC 3.1.6.13 iduronate-2-sulfatase
EC 3.1.6.14 N-acetylglucosamine-6-sulfatase
EC 3.1.6.15 N-sulfoglucosamine-3-sulfatase
EC 3.1.6.16 monomethyl-sulfatase
EC 3.1.6.17 D-lactate-2-sulfatase
EC 3.1.6.18 glucuronate-2-sulfatase
EC 3.1.6.19 (R)-specific secondary-alkylsulfatase
EC 3.1.6.20 S-sulfosulfanyl-L-cysteine sulfohydrolase

EC 3.1.7 Diphosphoric Monoester Hydrolases

EC 3.1.7.1 prenyl-diphosphatase
EC 3.1.7.2 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
EC 3.1.7.3 monoterpenyl-diphosphatase
EC 3.1.7.4 deleted, now covered by EC 4.2.1.133 and EC 4.2.3.141
EC 3.1.7.5 geranylgeranyl diphosphate diphosphatase
EC 3.1.7.6 farnesyl diphosphatase
EC 3.1.7.7 transferred now EC 4.2.3.194
EC 3.1.7.8 tuberculosinol synthase
EC 3.1.7.9 isotuberculosinol synthase
EC 3.1.7.10 (13E)-labda-7,13-dien-15-ol synthase
EC 3.1.7.11 geranyl diphosphate diphosphatase
EC 3.1.7.12 (+)-kolavelool synthase

EC 3.1.8 Phosphoric Triester Hydrolases

EC 3.1.8.1 aryldialkylphosphatase
EC 3.1.8.2 diisopropyl-fluorophosphatase

EC 3.1.11 Exodeoxyribonucleases Producing 5'-Phosphomonoesters

EC 3.1.11.1 exodeoxyribonuclease I
EC 3.1.11.2 exodeoxyribonuclease III
EC 3.1.11.3 exodeoxyribonuclease (lambda-induced)
EC 3.1.11.4 exodeoxyribonuclease (phage SP3-induced)
EC 3.1.11.5 exodeoxyribonuclease V
EC 3.1.11.6 exodeoxyribonuclease VII
EC 3.1.11.7 now EC 3.6.1.71
EC 3.1.11.8 now EC 3.6.1.70

EC 3.1.12 Exodeoxyribonucleases Producing 3'-Phosphomonoesters

EC 3.1.12.1 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming)
EC 3.1.12.2 now EC 3.6.1.72

EC 3.1.13 Exoribonucleases Producing 5'-Phosphomonoesters

EC 3.1.13.1 exoribonuclease II
EC 3.1.13.2 exoribonuclease H
EC 3.1.13.3 oligonucleotidase
EC 3.1.13.4 poly(A)-specific ribonuclease
EC 3.1.13.5 ribonuclease D

EC 3.1.14 Exoribonucleases Producing 3'-Phosphomonoesters

EC 3.1.14.1 yeast ribonuclease

EC 3.1.15 Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

EC 3.1.15.1 venom exonuclease

EC 3.1.16 Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

EC 3.1.16.1 spleen exonuclease

EC 3.1.21 Endodeoxyribonucleases Producing 5'-Phosphomonoesters

EC 3.1.21.1 deoxyribonuclease I
EC 3.1.21.2 deoxyribonuclease IV
EC 3.1.21.3 type I site-specific deoxyribonuclease
EC 3.1.21.4 type II site-specific deoxyribonuclease
EC 3.1.21.5 type III site-specific deoxyribonuclease
EC 3.1.21.6 CC-preferring endodeoxyribonuclease
EC 3.1.21.7 deoxyribonuclease V
EC 3.1.21.8 T4 deoxyribonuclease II
EC 3.1.21.9 T4 deoxyribonuclease IV

EC 3.1.22 Endodeoxyribonucleases Producing 3'-Phosphomonoesters

EC 3.1.22.1 deoxyribonuclease II
EC 3.1.22.2 Aspergillus deoxyribonuclease K1
EC 3.1.22.3 now EC 3.1.21.7
EC 3.1.22.4 crossover junction endodeoxyribonuclease
EC 3.1.22.5 deoxyribonuclease X

EC 3.1.23 and EC 3.1.24 now EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5
EC 3.1.25 Site-Specific Endodeoxyribonucleases Specific for Altered Bases

EC 3.1.25.1 deoxyribonuclease (pyrimidine dimer)
EC 3.1.25.2 now EC 4.2.99.18

EC 3.1.26 Endoribonucleases Producing 5'-Phosphomonoesters

EC 3.1.26.1 Physarum polycephalum ribonuclease
EC 3.1.26.2 ribonuclease alpha
EC 3.1.26.3 ribonuclease III
EC 3.1.26.4 ribonuclease H
EC 3.1.26.5 ribonuclease P
EC 3.1.26.6 ribonuclease IV
EC 3.1.26.7 ribonuclease P4
EC 3.1.26.8 ribonuclease M5
EC 3.1.26.9 ribonuclease [poly-(U)-specific]
EC 3.1.26.10 ribonuclease IX
EC 3.1.26.11 tRNase Z
EC 3.1.26.12 ribonuclease E
EC 3.1.26.13 retroviral ribonuclease H

EC 3.1.27 Endoribonucleases Producing 3'-Phosphomonoesters

EC 3.1.27.1 transferred now EC 4.6.1.19
EC 3.1.27.2 transferred now EC 4.6.1.22
EC 3.1.27.3 transferred now EC 4.6.1.24
EC 3.1.27.4 transferred now EC 4.6.1.20
EC 3.1.27.5 transferred now EC 4.6.1.18
EC 3.1.27.6 transferred now EC 4.6.1.21
EC 3.1.27.7 ribonuclease F
EC 3.1.27.8 ribonuclease V
EC 3.1.27.9 transferred now EC 4.6.1.16
EC 3.1.27.10 transferred now EC 4.6.1.23

EC 3.1.30 Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

EC 3.1.30.1 Aspergillus nuclease S1
EC 3.1.30.2 Serratia marcescens nuclease

EC 3.1.31 Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

EC 3.1.31.1 micrococcal nuclease

EC 3.2 Glycosylases

EC 3.2.1 Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds

EC 3.2.1.1 α-amylase
EC 3.2.1.2 β-amylase
EC 3.2.1.3 glucan 1,4-α-glucosidase
EC 3.2.1.4 cellulase
EC 3.2.1.5 deleted
EC 3.2.1.6 endo-1,3(4)-β-glucanase
EC 3.2.1.7 inulinase
EC 3.2.1.8 endo-1,4-β-xylanase
EC 3.2.1.9 deleted
EC 3.2.1.10 oligo-1,6-glucosidase
EC 3.2.1.11 dextranase
EC 3.2.1.12 deleted, included in EC 3.2.1.54
EC 3.2.1.13 deleted, included in EC 3.2.1.54
EC 3.2.1.14 chitinase
EC 3.2.1.15 endo-polygalacturonase
EC 3.2.1.16 deleted
EC 3.2.1.17 lysozyme
EC 3.2.1.18 exo-α-sialidase
EC 3.2.1.19 deleted
EC 3.2.1.20 α-glucosidase
EC 3.2.1.21 β-glucosidase
EC 3.2.1.22 α-galactosidase
EC 3.2.1.23 β-galactosidase
EC 3.2.1.24 α-mannosidase
EC 3.2.1.25 β-mannosidase
EC 3.2.1.26 β-fructofuranosidase
EC 3.2.1.27 deleted
EC 3.2.1.28 α,α-trehalase
EC 3.2.1.29 deleted, included in EC 3.2.1.52
EC 3.2.1.30 deleted, included in EC 3.2.1.52
EC 3.2.1.31 β-glucuronidase
EC 3.2.1.32 endo-1,3-β-xylanase
EC 3.2.1.33 amylo-1,6-glucosidase
EC 3.2.1.34 deleted, included in EC 3.2.1.35
EC 3.2.1.35 hyaluronoglucosaminidase
EC 3.2.1.36 hyaluronoglucuronidase
EC 3.2.1.37 xylan 1,4-β-xylosidase
EC 3.2.1.38 β-D-fucosidase
EC 3.2.1.39 glucan endo-1,3-β-D-glucosidase
EC 3.2.1.40 α-L-rhamnosidase
EC 3.2.1.41 pullulanase
EC 3.2.1.42 GDP-glucosidase
EC 3.2.1.43 β-L-rhamnosidase
EC 3.2.1.44 transferred now EC 3.2.1.211 and EC 3.2.1.212
EC 3.2.1.45 glucosylceramidase
EC 3.2.1.46 galactosylceramidase
EC 3.2.1.47 galactosylgalactosylglucosylceramidase
EC 3.2.1.48 sucrose α-glucosidase
EC 3.2.1.49 α-N-acetylgalactosaminidase
EC 3.2.1.50 α-N-acetylglucosaminidase
EC 3.2.1.51 α-L-fucosidase
EC 3.2.1.52 β-N-acetylhexosaminidase
EC 3.2.1.53 β-N-acetylgalactosaminidase
EC 3.2.1.54 cyclomaltodextrinase
EC 3.2.1.55 non-reducing end α-L-arabinofuranosidase
EC 3.2.1.56 glucuronosyl-disulfoglucosamine glucuronidase
EC 3.2.1.57 isopullulanase
EC 3.2.1.58 glucan 1,3-β-glucosidase
EC 3.2.1.59 glucan endo-1,3-α-glucosidase
EC 3.2.1.60 glucan 1,4-α-maltotetraohydrolase
EC 3.2.1.61 mycodextranase
EC 3.2.1.62 glycosylceramidase
EC 3.2.1.63 1,2-α-L-fucosidase
EC 3.2.1.64 2,6-β-fructan 6-levanbiohydrolase
EC 3.2.1.65 levanase
EC 3.2.1.66 quercitrinase
EC 3.2.1.67 galacturan 1,4-α-galacturonidase
EC 3.2.1.68 isoamylase
EC 3.2.1.69 deleted, included in EC 3.2.1.41
EC 3.2.1.70 glucan 1,6-α-glucosidase
EC 3.2.1.71 glucan endo-1,2-β-glucosidase
EC 3.2.1.72 xylan 1,3-β-xylosidase
EC 3.2.1.73 licheninase
EC 3.2.1.74 glucan 1,4-β-glucosidase
EC 3.2.1.75 glucan endo-1,6-β-glucosidase
EC 3.2.1.76 L-iduronidase
EC 3.2.1.77 mannan 1,2-(1,3)-α-mannosidase
EC 3.2.1.78 mannan endo-1,4-β-mannosidase
EC 3.2.1.79 deleted, included in EC 3.2.1.55
EC 3.2.1.80 fructan β-fructosidase
EC 3.2.1.81 β-agarase
EC 3.2.1.82 exo-poly-α-galacturonosidase
EC 3.2.1.83 κ-carrageenase
EC 3.2.1.84 glucan 1,3-α-glucosidase
EC 3.2.1.85 6-phospho-β-galactosidase
EC 3.2.1.86 6-phospho-β-glucosidase
EC 3.2.1.87 capsular-polysaccharide endo-1,3-α-galactosidase
EC 3.2.1.88 non-reducing end β-L-arabinopyranosidase
EC 3.2.1.89 arabinogalactan endo-β-1,4-galactanase
EC 3.2.1.90Deleted, not sufficiently characterised.
EC 3.2.1.91 cellulose 1,4-β-cellobiosidase (non-reducing end)
EC 3.2.1.92 peptidoglycan β-N-acetylmuramidase
EC 3.2.1.93 α,α-phosphotrehalase
EC 3.2.1.94 glucan 1,6-α-isomaltosidase
EC 3.2.1.95 dextran 1,6-α-isomaltotriosidase
EC 3.2.1.96 mannosyl-glycoprotein endo-β-N-acetylglucosaminidase
EC 3.2.1.97 endo-α-N-acetylgalactosaminidase
EC 3.2.1.98 glucan 1,4-α-maltohexaosidase
EC 3.2.1.99 arabinan endo-1,5-α-L-arabinanase
EC 3.2.1.100 mannan 1,4-mannobiosidase
EC 3.2.1.101 mannan endo-1,6-α-mannosidase
EC 3.2.1.102 blood-group-substance endo-1,4-β-galactosidase
EC 3.2.1.103 keratan-sulfate endo-1,4-β-galactosidase
EC 3.2.1.104 steryl-β-glucosidase
EC 3.2.1.105 strictosidine β-glucosidase
EC 3.2.1.106 mannosyl-oligosaccharide glucosidase
EC 3.2.1.107 protein-glucosylgalactosylhydroxylysine glucosidase
EC 3.2.1.108 lactase
EC 3.2.1.109 endogalactosaminidase
EC 3.2.1.110 deleted identical to EC 3.2.1.97
EC 3.2.1.111 1,3-α-L-fucosidase
EC 3.2.1.112 2-deoxyglucosidase
EC 3.2.1.113 mannosyl-oligosaccharide 1,2-α-mannosidase
EC 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-α-mannosidase
EC 3.2.1.115 branched-dextran exo-1,2-α-glucosidase
EC 3.2.1.116 glucan 1,4-α-maltotriohydrolase
EC 3.2.1.117 amygdalin β-glucosidase
EC 3.2.1.118 prunasin β-glucosidase
EC 3.2.1.119 vicianin β-glucosidase
EC 3.2.1.120 oligoxyloglucan β-glycosidase
EC 3.2.1.121 polymannuronate hydrolase
EC 3.2.1.122 maltose-6'-phosphate glucosidase
EC 3.2.1.123 endoglycosylceramidase
EC 3.2.1.124 3-deoxy-2-octulosonidase
EC 3.2.1.125 raucaffricine β-glucosidase
EC 3.2.1.126 coniferin β-glucosidase
EC 3.2.1.127 1,6-α-L-fucosidase
EC 3.2.1.128 glycyrrhizinate β-glucuronidase
EC 3.2.1.129 endo-α-sialidase
EC 3.2.1.130 glycoprotein endo-α-1,2-mannosidase
EC 3.2.1.131 xylan α-1,2-glucuronosidase
EC 3.2.1.132 chitosanase
EC 3.2.1.133 glucan 1,4-α-maltohydrolase
EC 3.2.1.134 difructose-anhydride synthase
EC 3.2.1.135 neopullulanase
EC 3.2.1.136 glucuronoarabinoxylan endo-1,4-β-xylanase
EC 3.2.1.137 mannan exo-1,2-1,6-α-mannosidase
EC 3.2.1.138 now EC 4.2.2.15
EC 3.2.1.139 α-glucuronidase
EC 3.2.1.140 lacto-N-biosidase
EC 3.2.1.141 4-α-D-{(1→4)-α-D-glucano}trehalose trehalohydrolase
EC 3.2.1.142 limit dextrinase
EC 3.2.1.143 poly(ADP-ribose) glycohydrolase
EC 3.2.1.144 3-deoxyoctulosonase
EC 3.2.1.145 galactan 1,3-β-galactosidase
EC 3.2.1.146 β-galactofuranosidase
EC 3.2.1.147 thioglucosidase
EC 3.2.1.148 now EC 4.4.1.21
EC 3.2.1.149 β-primeverosidase
EC 3.2.1.150 oligoxyloglucan reducing-end-specific cellobiohydrolase
EC 3.2.1.151 xyloglucan-specific endo-β-1,4-glucanase
EC 3.2.1.152 mannosylglycoprotein endo-β-mannosidase
EC 3.2.1.153 fructan β-(2,1)-fructosidase
EC 3.2.1.154 fructan β-(2,6)-fructosidase
EC 3.2.1.155 xyloglucan-specific endo-processive β-1,4-glucanase
EC 3.2.1.156 oligosaccharide reducing-end xylanase
EC 3.2.1.157 ι-carrageenase
EC 3.2.1.158 α-agarase
EC 3.2.1.159 α-neoagaro-oligosaccharide hydrolase
EC 3.2.1.160 deleted, identical to EC 3.2.1.155
EC 3.2.1.161 β-apiosyl-β-glucosidase
EC 3.2.1.162 λ-carrageenase
EC 3.2.1.163 1,6-α-D-mannosidase
EC 3.2.1.164 galactan endo-1,6-β-galactosidase
EC 3.2.1.165 exo-1,4-β-D-glucosaminidase
EC 3.2.1.166 heparanase
EC 3.2.1.167 baicalin-β-D-glucuronidase
EC 3.2.1.168 hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase
EC 3.2.1.169 protein O-GlcNAcase
EC 3.2.1.170 mannosylglycerate hydrolase
EC 3.2.1.171 rhamnogalacturonan hydrolase
EC 3.2.1.172 unsaturated rhamnogalacturonyl hydrolase
EC 3.2.1.173 rhamnogalacturonan galacturonohydrolase
EC 3.2.1.174 rhamnogalacturonan rhamnohydrolase
EC 3.2.1.175 β-D-glucopyranosyl abscisate β-glucosidase
EC 3.2.1.176 cellulose 1,4-β-cellobiosidase (reducing end)
EC 3.2.1.177 α-D-xyloside xylohydrolase
EC 3.2.1.178 β-porphyranase
EC 3.2.1.179 gellan tetrasaccharide unsaturated glucuronyl hydrolase
EC 3.2.1.180 unsaturated chondroitin disaccharide hydrolase
EC 3.2.1.181 galactan endo-β-1,3-galactanase
EC 3.2.1.182 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside β-D-glucosidase
EC 3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
EC 3.2.1.184 UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing)
EC 3.2.1.185 non-reducing end β-L-arabinofuranosidase
EC 3.2.1.186 protodioscin 26-O-β-D-glucosidase
EC 3.2.1.187 (Ara-f)3-Hyp β-L-arabinobiosidase
EC 3.2.1.188 avenacosidase
EC 3.2.1.189 dioscin glycosidase (diosgenin-forming)
EC 3.2.1.190 dioscin glycosidase (3-O-β-D-Glc-diosgenin-forming)
EC 3.2.1.191 ginsenosidase type III
EC 3.2.1.192 ginsenoside Rb1 β-glucosidase
EC 3.2.1.193 ginsenosidase type I
EC 3.2.1.194 ginsenosidase type IV
EC 3.2.1.195 20-O-multi-glycoside ginsenosidase
EC 3.2.1.196 limit dextrin α-1,6-maltotetraose-hydrolase
EC 3.2.1.197 β-1,2-mannosidase
EC 3.2.1.198 α-mannan endo-1,2-α-mannanase
EC 3.2.1.199 sulfoquinovosidase
EC 3.2.1.200 exo-chitinase (non-reducing end)
EC 3.2.1.201 exo-chitinase (reducing end)
EC 3.2.1.202 endo-chitodextinase
EC 3.2.1.203 carboxymethylcellulase
EC 3.2.1.204 1,3-α-isomaltosidase
EC 3.2.1.205 isomaltose glucohydrolase
EC 3.2.1.206 oleuropein β-glucosidase
EC 3.2.1.207 mannosyl-oligosaccharide α-1,3-glucosidase
EC 3.2.1.208 glucosylglycerate hydrolase
EC 3.2.1.209 endoplasmic reticulum Man9GlcNAc2 1,2-α-mannosidase
EC 3.2.1.210 endoplasmic reticulum Man8GlcNAc2 1,2-α-mannosidase
EC 3.2.1.211 endo-(1→3)-fucoidanase
EC 3.2.1.212 endo-(1→4)-fucoidanase
EC 3.2.1.213 galactan exo-1,6-β-galactobiohydrolase (non-reducing end)

EC 3.2.2 Hydrolysing N-Glycosyl Compounds

EC 3.2.2.1 purine nucleosidase
EC 3.2.2.2 inosine nucleosidase
EC 3.2.2.3 uridine nucleosidase
EC 3.2.2.4 AMP nucleosidase
EC 3.2.2.5 NAD+ glycohydrolase
EC 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
EC 3.2.2.7 adenosine nucleosidase
EC 3.2.2.8 ribosylpyrimidine nucleosidase
EC 3.2.2.9 adenosylhomocysteine nucleosidase
EC 3.2.2.10 pyrimidine-5'-nucleotide nucleosidase
EC 3.2.2.11 β-aspartyl-N-acetylglucosaminidase
EC 3.2.2.12 inosinate nucleosidase
EC 3.2.2.13 1-methyladenosine nucleosidase
EC 3.2.2.14 NMN nucleosidase
EC 3.2.2.15 DNA-deoxyinosine glycosylase
EC 3.2.2.16 methylthioadenosine nucleosidase
EC 3.2.2.17 deoxyribodipyrimidine endonucleosidase
EC 3.2.2.18 deleted, included in EC 3.5.1.52
EC 3.2.2.19 ADP-ribosylarginine hydrolase
EC 3.2.2.20 DNA-3-methyladenine glycosylase I
EC 3.2.2.21 DNA-3-methyladenine glycosylase II
EC 3.2.2.22 rRNA N-glycosylase
EC 3.2.2.23 DNA-formamidopyrimidine glycosylase
EC 3.2.2.24 ADP-ribosyl-[dinitrogen reductase] hydrolase
EC 3.2.2.25 N-methyl nucleosidase
EC 3.2.2.26 futalosine hydrolase
EC 3.2.2.27 uracil-DNA glycosylase
EC 3.2.2.28 double-stranded uracil-DNA glycosylase
EC 3.2.2.29 thymine-DNA glycosylase
EC 3.2.2.30 aminodeoxyfutalosine nucleosidase
EC 3.2.2.31 adenine glycosylase

EC 3.2.3 Hydrolysing S-Glycosyl Compounds

EC 3.2.3.1 now EC 3.2.1.147

EC 3.3 Acting on Ether Bonds

EC 3.3.1 Thioether and trialkylsulfonium hydrolases

EC 3.3.1.1 adenosylhomocysteinase
EC 3.3.1.2 S-adenosyl-L-methionine hydrolase (L-homoserine-forming)
EC 3.3.1.3 now EC 3.2.1.148

EC 3.3.2 Ether Hydrolases

EC 3.3.2.1 isochorismatase
EC 3.3.2.2 lysoplasmalogenase
EC 3.3.2.3 now considered mixture of EC 3.3.2.9) and EC 3.3.2.10
EC 3.3.2.4 trans-epoxysuccinate hydrolase
EC 3.3.2.5 transferred now covered by EC 3.3.2.2
EC 3.3.2.6 leukotriene-A4 hydrolase
EC 3.3.2.7 hepoxilin-epoxide hydrolase
EC 3.3.2.8 limonene-1,2-epoxide hydrolase
EC 3.3.2.9 microsomal epoxide hydrolase
EC 3.3.2.10 soluble epoxide hydrolase
EC 3.3.2.11 cholesterol-5,6-oxide hydrolase
EC 3.3.2.12 oxepin-CoA hydrolase
EC 3.3.2.13 chorismatase
EC 3.3.2.14 2,4-dinitroanisole O-demethylase
EC 3.3.2.15 trans-2,3-dihydro-3-hydroxyanthranilic acid synthase

EC 3.4 Acting on peptide bonds (Peptidases)

EC 3.4.1 α-Amino-Acyl-Peptide Hydrolases (discontinued)

EC 3.4.1.1 now EC 3.4.11.1
EC 3.4.1.2 now EC 3.4.11.2
EC 3.4.1.3 now EC 3.4.11.4
EC 3.4.1.4 now EC 3.4.11.5

EC 3.4.2 Peptidyl-Amino-Acid Hydrolases (discontinued)

EC 3.4.2.1 now EC 3.4.17.1
EC 3.4.2.2 now EC 3.4.17.2
EC 3.4.2.3 now EC 3.4.17.4

EC 3.4.3 Dipeptide Hydrolases (discontinued)

EC 3.4.3.1 now EC 3.4.13.18
EC 3.4.3.2 now EC 3.4.13.18
EC 3.4.3.3 now EC 3.4.13.3
EC 3.4.3.4 now EC 3.4.13.5
EC 3.4.3.5 now EC 3.4.13.6
EC 3.4.3.6 now EC 3.4.13.8
EC 3.4.3.7 now EC 3.4.13.9

EC 3.4.4 Peptidyl Peptide Hydrolases (discontinued)

EC 3.4.4.1 now EC 3.4.23.1
EC 3.4.4.2 now EC 3.4.23.2
EC 3.4.4.3 now EC 3.4.23.4
EC 3.4.4.4 now EC 3.4.21.4
EC 3.4.4.5 now EC 3.4.21.1
EC 3.4.4.6 now EC 3.4.21.1
EC 3.4.4.7 now covered by EC 3.4.21.36, EC 3.4.21.37
EC 3.4.4.8 now EC 3.4.21.9
EC 3.4.4.9 now EC 3.4.14.1
EC 3.4.4.10 now EC 3.4.22.2
EC 3.4.4.11 now EC 3.4.22.6
EC 3.4.4.12 now EC 3.4.22.3
EC 3.4.4.13 now EC 3.4.21.5
EC 3.4.4.14 now EC 3.4.21.7
EC 3.4.4.15 now EC 3.4.23.15
EC 3.4.4.16 now covered by EC 3.4.21.62 to EC 3.4.21.67
EC 3.4.4.17 now covered by EC 3.4.23.20 to EC 3.4.23.30
EC 3.4.4.18 now EC 3.4.22.10
EC 3.4.4.19 now EC 3.4.24.3
EC 3.4.4.20 now EC 3.4.22.8
EC 3.4.4.21 now EC 3.4.21.34
EC 3.4.4.22 now EC 3.4.23.3
EC 3.4.4.23 now EC 3.4.23.5
EC 3.4.4.24 now covered by EC 3.4.22.32 and EC 3.4.22.33
EC 3.4.4.25 deleted

EC 3.4.11 Aminopeptidases

EC 3.4.11.1 leucyl aminopeptidase
EC 3.4.11.2 membrane alanyl aminopeptidase
EC 3.4.11.3 cystinyl aminopeptidase
EC 3.4.11.4 tripeptide aminopeptidase
EC 3.4.11.5 prolyl aminopeptidase
EC 3.4.11.6 arginyl aminopeptidase
EC 3.4.11.7 glutamyl aminopeptidase
EC 3.4.11.8 now EC 3.4.19.3
EC 3.4.11.9 Xaa-Pro aminopeptidase
EC 3.4.11.10 bacterial leucyl aminopeptidase
EC 3.4.11.11 deleted
EC 3.4.11.12 deleted (Supplement 4)
EC 3.4.11.13 clostridial aminopeptidase
EC 3.4.11.14 cytosol alanyl aminopeptidase
EC 3.4.11.15 lysyl aminopeptidase
EC 3.4.11.16 Xaa-Trp aminopeptidase
EC 3.4.11.17 tryptophanyl aminopeptidase
EC 3.4.11.18 methionyl aminopeptidase
EC 3.4.11.19 D-stereospecific aminopeptidase
EC 3.4.11.20 aminopeptidase Ey
EC 3.4.11.21 aspartyl aminopeptidase
EC 3.4.11.22 aminopeptidase I
EC 3.4.11.23 PepB aminopeptidase
EC 3.4.11.24 aminopeptidase S
EC 3.4.11.25 β-peptidyl aminopeptidase
EC 3.4.11.26 intermediate cleaving peptidase 55

EC 3.4.12 Peptidylamino-Acid Hydrolases or Acylamino-Acid Hydrolases

EC 3.4.12.1 now EC 3.4.16.1
EC 3.4.12.2 now EC 3.4.17.1
EC 3.4.12.3 now EC 3.4.17.2
EC 3.4.12.4 now EC 3.4.16.2
EC 3.4.12.5 now EC 3.4.19.10
EC 3.4.12.6 now EC 3.4.17.8
EC 3.4.12.7 now EC 3.4.17.3
EC 3.4.12.8 now EC 3.4.17.4
EC 3.4.12.9 deleted
EC 3.4.12.10 now EC 3.4.19.9
EC 3.4.12.11 now EC 3.4.17.6
EC 3.4.12.12 now EC 3.4.16.1
EC 3.4.12.13 deleted

EC 3.4.13 Dipeptidases

EC 3.4.13.1 now EC 3.4.13.18
EC 3.4.13.2 now EC 3.4.13.18
EC 3.4.13.3 deleted, covered by EC 3.4.13.18 and EC 3.4.13.20
EC 3.4.13.4 Xaa-Arg dipeptidase
EC 3.4.13.5 Xaa-methyl-His dipeptidase
EC 3.4.13.6 now EC 3.4.11.2 (Supplement 4)
EC 3.4.13.7 Glu-Glu dipeptidase
EC 3.4.13.8 now EC 3.4.17.21 (Supplement 6)
EC 3.4.13.9 Xaa-Pro dipeptidase
EC 3.4.13.10 now EC 3.4.19.5
EC 3.4.13.11 deleted, included in EC 3.4.13.18
EC 3.4.13.12 Met-Xaa dipeptidase
EC 3.4.13.13 deleted, included in EC 3.4.13.3
EC 3.4.13.14 deleted
EC 3.4.13.15 deleted, included in EC 3.4.13.18
EC 3.4.13.16 deleted
EC 3.4.13.17 non-stereospecific dipeptidase
EC 3.4.13.18 cytosol nonspecific dipeptidase
EC 3.4.13.19 membrane dipeptidase
EC 3.4.13.20 β-Ala-His dipeptidase
EC 3.4.13.21 dipeptidase E
EC 3.4.13.22 D-Ala-D-Ala dipeptidase
EC 3.4.13.23 cysteinylglycine-S-conjugate dipeptidase

EC 3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases

EC 3.4.14.1 dipeptidyl-peptidase I
EC 3.4.14.2 dipeptidyl-peptidase II
EC 3.4.14.3 now EC 3.4.19.1
EC 3.4.14.4 dipeptidyl-peptidase III
EC 3.4.14.5 dipeptidyl-peptidase IV
EC 3.4.14.6 dipeptidyl-dipeptidase
EC 3.4.14.7 deleted
EC 3.4.14.8 now covered by EC 3.4.14.9, EC 3.4.14.10
EC 3.4.14.9 tripeptidyl-peptidase I
EC 3.4.14.10 tripeptidyl-peptidase II
EC 3.4.14.11 Xaa-Pro dipeptidyl-peptidase
EC 3.4.14.12 prolyltripeptidyl aminopeptidase
EC 3.4.14.13 γ-D-glutamyl-L-lysine dipeptidyl-peptidase

EC 3.4.15 Peptidyl-dipeptidases

EC 3.4.15.1 peptidyl-dipeptidase A
EC 3.4.15.2 now EC 3.4.19.2
EC 3.4.15.3 deleted, included in EC 3.4.15.5 (supplement 2)
EC 3.4.15.4 peptidyl-dipeptidase B
EC 3.4.15.5 peptidyl-dipeptidase Dcp
EC 3.4.15.6 cyanophycinase

EC 3.4.16 Serine-type carboxypeptidases

EC 3.4.16.1 deleted, included in EC 3.4.16.5, EC 3.4.16.6 (supplement 1)
EC 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase
EC 3.4.16.3 deleted, included in EC 3.4.16.5 (supplement 1)
EC 3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
EC 3.4.16.5 carboxypeptidase C
EC 3.4.16.6 carboxypeptidase D

EC 3.4.17 Metallocarboxypeptidases

EC 3.4.17.1 carboxypeptidase A
EC 3.4.17.2 carboxypeptidase B
EC 3.4.17.3 lysine carboxypeptidase
EC 3.4.17.4 Gly-Xaa carboxypeptidase
EC 3.4.17.5 deleted
EC 3.4.17.6 alanine carboxypeptidase
EC 3.4.17.7 now EC 3.4.19.10
EC 3.4.17.8 muramoylpentapeptide carboxypeptidase
EC 3.4.17.9 deleted, included in EC 3.4.17.4
EC 3.4.17.10 carboxypeptidase E
EC 3.4.17.11 glutamate carboxypeptidase
EC 3.4.17.12 carboxypeptidase M
EC 3.4.17.13 muramoyltetrapeptide carboxypeptidase
EC 3.4.17.14 zinc D-Ala-D-Ala carboxypeptidase
EC 3.4.17.15 carboxypeptidase A2
EC 3.4.17.16 membrane Pro-Xaa carboxypeptidase
EC 3.4.17.17 tubulinyl-Tyr carboxypeptidase
EC 3.4.17.18 carboxypeptidase T
EC 3.4.17.19 carboxypeptidase Taq
EC 3.4.17.20 carboxypeptidase U
EC 3.4.17.21 glutamate carboxypeptidase II
EC 3.4.17.22 metallocarboxypeptidase D
EC 3.4.17.23 angiotensin-converting enzyme 2
EC 3.4.17.24 tubulin-glutamate carboxypeptidase

EC 3.4.18 Cysteine-type carboxypeptidases

EC 3.4.18.1 cathepsin X

EC 3.4.19 Omega peptidases

EC 3.4.19.1 acylaminoacyl-peptidase
EC 3.4.19.2 peptidyl-glycinamidase
EC 3.4.19.3 pyroglutamyl-peptidase I
EC 3.4.19.4 deleted
EC 3.4.19.5 β-aspartyl-peptidase
EC 3.4.19.6 pyroglutamyl-peptidase II
EC 3.4.19.7 N-formylmethionyl-peptidase
EC 3.4.19.8 now EC 3.4.17.21 (Supplement 6)
EC 3.4.19.9 folate γ-glutamyl hydrolase
EC 3.4.19.10 now EC 3.5.1.28 (Supplement 4)
EC 3.4.19.11 γ-D-glutamyl-meso-diaminopimelate peptidase I
EC 3.4.19.12 ubiquitinyl hydrolase 1
EC 3.4.19.13 glutathione γ-glutamate hydrolase
EC 3.4.19.14 leukotriene-C4 hydrolase
EC 3.4.19.15 desampylase
EC 3.4.19.16 glucosinolate γ-glutamyl hydrolase

EC 3.4.21 Serine endopeptidases

EC 3.4.21.1 chymotrypsin
EC 3.4.21.2 chymotrypsin C
EC 3.4.21.3 metridin
EC 3.4.21.4 trypsin
EC 3.4.21.5 thrombin
EC 3.4.21.6 coagulation factor Xa
EC 3.4.21.7 plasmin
EC 3.4.21.8 now covered by EC 3.4.21.34 and EC 3.4.21.35
EC 3.4.21.9 enteropeptidase
EC 3.4.21.10 acrosin
EC 3.4.21.11 now covered by EC 3.4.21.36 and EC 3.4.21.37
EC 3.4.21.12 α-Lytic endopeptidase
EC 3.4.21.13 now EC 3.4.16.1
EC 3.4.21.14 now covered by EC 3.4.21.62 to EC 3.4.21.65 and EC 3.4.21.67
EC 3.4.21.15 now EC 3.4.21.63
EC 3.4.21.16 deleted
EC 3.4.21.17 deleted
EC 3.4.21.18 deleted
EC 3.4.21.19 glutamyl endopeptidase
EC 3.4.21.20 cathepsin G
EC 3.4.21.21 coagulation factor VIIa
EC 3.4.21.22 coagulation factor IXa
EC 3.4.21.23 deleted
EC 3.4.21.24 deleted
EC 3.4.21.25 cucumisin
EC 3.4.21.26 prolyl oligopeptidase
EC 3.4.21.27 coagulation factor XIa
EC 3.4.21.28 deleted, included in EC 3.4.21.74
EC 3.4.21.29 deleted, included in EC 3.4.21.74
EC 3.4.21.30 deleted, included in EC 3.4.21.74
EC 3.4.21.31 now covered by EC 3.4.21.68 and EC 3.4.21.73
EC 3.4.21.32 brachyurin
EC 3.4.21.33 deleted
EC 3.4.21.34 plasma kallikrein
EC 3.4.21.35 tissue kallikrein
EC 3.4.21.36 pancreatic elastase
EC 3.4.21.37 leukocyte elastase
EC 3.4.21.38 coagulation factor XIIa
EC 3.4.21.39 chymase
EC 3.4.21.40 deleted
EC 3.4.21.41 complement subcomponent C
EC 3.4.21.42 complement subcomponent C
EC 3.4.21.43 classical-complement-pathway C3/C5 convertase
EC 3.4.21.44 deleted, included in EC 3.4.21.43
EC 3.4.21.45 complement factor I
EC 3.4.21.46 complement factor D
EC 3.4.21.47 alternative-complement-pathway C3/C5 convertase
EC 3.4.21.48 cerevisin
EC 3.4.21.49 hypodermin C
EC 3.4.21.50 lysyl endopeptidase
EC 3.4.21.51 deleted
EC 3.4.21.52 deleted
EC 3.4.21.53 endopeptidase La
EC 3.4.21.54 γ-renin
EC 3.4.21.55 venombin AB
EC 3.4.21.56 deleted
EC 3.4.21.57 leucyl endopeptidase
EC 3.4.21.58 deleted
EC 3.4.21.59 tryptase
EC 3.4.21.60 scutelarin
EC 3.4.21.61 kexin
EC 3.4.21.62 subtilisin
EC 3.4.21.63 oryzin
EC 3.4.21.64 peptidase K
EC 3.4.21.65 thermomycolin
EC 3.4.21.66 thermitase
EC 3.4.21.67 endopeptidase So
EC 3.4.21.68 t-plasminogen activator
EC 3.4.21.69 protein C (activated)
EC 3.4.21.70 pancreatic endopeptidase E
EC 3.4.21.71 pancreatic elastase II
EC 3.4.21.72 IgA-specific serine endopeptidase
EC 3.4.21.73 u-plasminogen activator
EC 3.4.21.74 venombin A
EC 3.4.21.75 furin
EC 3.4.21.76 myeloblastin
EC 3.4.21.77 semenogelase
EC 3.4.21.78 granzyme A
EC 3.4.21.79 granzyme B
EC 3.4.21.80 streptogrisin A
EC 3.4.21.81 streptogrisin B
EC 3.4.21.82 glutamyl endopeptidase II
EC 3.4.21.83 oligopeptidase B
EC 3.4.21.84 limulus clotting factor
EC 3.4.21.85 limulus clotting factor
EC 3.4.21.86 limulus clotting enzyme
EC 3.4.21.87 now EC 3.4.23.49
EC 3.4.21.88 repressor LexA
EC 3.4.21.89 signal peptidase I
EC 3.4.21.90 togavirin
EC 3.4.21.91 flavivirin
EC 3.4.21.92 endopeptidase Clp
EC 3.4.21.93 proprotein convertase 1
EC 3.4.21.94 proprotein convertase 2
EC 3.4.21.95 snake venom factor V activator
EC 3.4.21.96 lactocepin
EC 3.4.21.97 assemblin
EC 3.4.21.98 hepacivirin
EC 3.4.21.99 spermosin
EC 3.4.21.100 sedolisin
EC 3.4.21.101 xanthomonalisin
EC 3.4.21.102 C-terminal processing peptidase
EC 3.4.21.103 physarolisin
EC 3.4.21.104 mannan-binding lectin-associated serine protease-2
EC 3.4.21.105 rhomboid protease
EC 3.4.21.106 hepsin
EC 3.4.21.107 peptidase Do
EC 3.4.21.108 HtrA2 peptidase
EC 3.4.21.109 matriptase
EC 3.4.21.110 C5a peptidase
EC 3.4.21.111 aqualysin 1
EC 3.4.21.112 site-1 protease
EC 3.4.21.113 pestivirus NS3 polyprotein peptidase
EC 3.4.21.114 equine arterivirus serine peptidase
EC 3.4.21.115 infectious pancreatic necrosis birnavirus Vp4 peptidase
EC 3.4.21.116 SpoIVB peptidase
EC 3.4.21.117 stratum corneum chymotryptic enzyme
EC 3.4.21.118 kallikrein 8
EC 3.4.21.119 kallikrein 13
EC 3.4.21.120 oviductin
EC 3.4.21.121 Lys-Lys/Arg-Xaa endopeptidase

EC 3.4.22 Cysteine endopeptidases

EC 3.4.22.1 cathepsin B
EC 3.4.22.2 papain
EC 3.4.22.3 ficain
EC 3.4.22.4 now covered by EC 3.4.22.32 and EC 3.4.22.33
EC 3.4.22.5 now EC 3.4.22.33
EC 3.4.22.6 chymopapain
EC 3.4.22.7 asclepain
EC 3.4.22.8 clostripain
EC 3.4.22.9 now EC 3.4.21.48
EC 3.4.22.10 streptopain
EC 3.4.22.11 now EC 3.4.24.56 (supplement 3)
EC 3.4.22.12 now EC 3.4.19.9
EC 3.4.22.13 deleted
EC 3.4.22.14 actinidain
EC 3.4.22.15 cathepsin L
EC 3.4.22.16 cathepsin H
EC 3.4.22.17 now EC 3.4.22.52 and EC 3.4.22.53
EC 3.4.22.18 deleted, included in EC 3.4.21.26
EC 3.4.22.19 deleted, included in EC 3.4.24.15
EC 3.4.22.20 deleted
EC 3.4.22.21 deleted, included in EC 3.4.99.46
EC 3.4.22.22 now EC 3.4.24.37
EC 3.4.22.23 deleted, included in EC 3.4.21.61
EC 3.4.22.24 cathepsin T
EC 3.4.22.25 glycyl endopeptidase
EC 3.4.22.26 cancer procoagulant
EC 3.4.22.27 cathepsin S
EC 3.4.22.28 picornain 3C
EC 3.4.22.29 picornain 2A
EC 3.4.22.30 caricain
EC 3.4.22.31 ananain
EC 3.4.22.32 stem bromelain
EC 3.4.22.33 fruit bromelain
EC 3.4.22.34 legumain
EC 3.4.22.35 histolysain
EC 3.4.22.36 caspase-1
EC 3.4.22.37 gingipain R
EC 3.4.22.38 cathepsin K
EC 3.4.22.39 adenain
EC 3.4.22.40 bleomycin hydrolase
EC 3.4.22.41 cathepsin F
EC 3.4.22.42 cathepsin O
EC 3.4.22.43 cathepsin V
EC 3.4.22.44 nuclear-inclusion-a endopeptidase
EC 3.4.22.45 helper-component proteinase
EC 3.4.22.46 L-peptidase EC 3.4.22.47 gingipain K
EC 3.4.22.48 staphopain
EC 3.4.22.49 separase
EC 3.4.22.50 V-cath endopeptidase
EC 3.4.22.51 cruzipain
EC 3.4.22.52 calpain-1
EC 3.4.22.53 calpain-2
EC 3.4.22.54 calpain-3
EC 3.4.22.55 caspase-2
EC 3.4.22.56 caspase-3
EC 3.4.22.57 caspase-4
EC 3.4.22.58 caspase-5
EC 3.4.22.59 caspase-6
EC 3.4.22.60 caspase-7
EC 3.4.22.61 caspase-8
EC 3.4.22.62 caspase-9
EC 3.4.22.63 caspase-10
EC 3.4.22.64 caspase-11
EC 3.4.22.65 peptidase 1 (mite)
EC 3.4.22.66 calicivirin
EC 3.4.22.67 zingipain
EC 3.4.22.68 Ulp1 peptidase
EC 3.4.22.69 SARS coronavirus main proteinase
EC 3.4.22.70 sortase A
EC 3.4.22.71 sortase B

EC 3.4.23 Aspartic endopeptidases

EC 3.4.23.1 pepsin A
EC 3.4.23.2 pepsin B
EC 3.4.23.3 gastricsin
EC 3.4.23.4 chymosin
EC 3.4.23.5 cathepsin D
EC 3.4.23.6 now covered by EC 3.4.23.18 to EC 3.4.23.28 and EC 3.4.23.30
EC 3.4.23.7 now EC 3.4.23.20
EC 3.4.23.8 now EC 3.4.23.25
EC 3.4.23.9 now EC 3.4.23.21
EC 3.4.23.10 now EC 3.4.23.22
EC 3.4.23.11 deleted
EC 3.4.23.12 nepenthesin
EC 3.4.23.13 deleted
EC 3.4.23.14 deleted
EC 3.4.23.15 renin
EC 3.4.23.16 HIV-1 retropepsin
EC 3.4.23.17 Pro-opiomelanocortin converting enzyme
EC 3.4.23.18 aspergillopepsin I
EC 3.4.23.19 aspergillopepsin II
EC 3.4.23.20 penicillopepsin
EC 3.4.23.21 rhizopuspepsin
EC 3.4.23.22 endothiapepsin
EC 3.4.23.23 mucorpepsin
EC 3.4.23.24 candidapepsin
EC 3.4.23.25 saccharopepsin
EC 3.4.23.26 rhodotorulapepsin
EC 3.4.23.27 now EC 3.4.21.103
EC 3.4.23.28 acrocylindropepsin
EC 3.4.23.29 polyporopepsin
EC 3.4.23.30 pycnoporopepsin
EC 3.4.23.31 scytalidopepsin A
EC 3.4.23.32 scytalidopepsin B
EC 3.4.23.33 now EC 3.4.21.101
EC 3.4.23.34 cathepsin E
EC 3.4.23.35 barrierpepsin
EC 3.4.23.36 signal peptidase II
EC 3.4.23.37 now EC 3.4.21.100
EC 3.4.23.38 plasmepsin I
EC 3.4.23.39 plasmepsin II
EC 3.4.23.40 phytepsin
EC 3.4.23.41 yapsin 1
EC 3.4.23.42 thermopsin
EC 3.4.23.43 prepilin peptidase
EC 3.4.23.44 nodavirus endopeptidase
EC 3.4.23.45 memapsin 1
EC 3.4.23.46 memapsin 2
EC 3.4.23.47 HIV-2 retropepsin
EC 3.4.23.48 plasminogen activator Pla
EC 3.4.23.49 omptin
EC 3.4.23.50 human endogenous retrovirus K endopeptidase
EC 3.4.23.51 HycI peptidase
EC 3.4.23.52 preflagellin peptidase

EC 3.4.24 Metalloendopeptidases

EC 3.4.24.1 atrolysin A
EC 3.4.24.2 deleted
EC 3.4.24.3 microbial collagenase
EC 3.4.24.4 now covered by EC 3.4.24.25 to EC 3.4.24.32, EC 3.4.24.39 and EC 3.4.24.40
EC 3.4.24.5 now covered by EC 3.4.22.17 and EC 3.4.25.1
EC 3.4.24.6 leucolysin
EC 3.4.24.7 interstitial collagenase
EC 3.4.24.8 deleted, included in EC 3.4.24.3
EC 3.4.24.9 deleted
EC 3.4.24.10 deleted
EC 3.4.24.11 neprilysin
EC 3.4.24.12 envelysin
EC 3.4.24.13 IgA-specific metalloendopeptidase
EC 3.4.24.14 procollagen N-endopeptidase
EC 3.4.24.15 thimet oligopeptidase
EC 3.4.24.16 neurolysin
EC 3.4.24.17 stromelysin 1
EC 3.4.24.18 meprin A
EC 3.4.24.19 procollagen C-endopeptidase
EC 3.4.24.20 peptidyl-Lys metalloendopeptidase
EC 3.4.24.21 astacin
EC 3.4.24.22 stromelysin 2
EC 3.4.24.23 matrilysin
EC 3.4.24.24 gelatinase A
EC 3.4.24.25 vibriolysin
EC 3.4.24.26 pseudolysin
EC 3.4.24.27 thermolysin
EC 3.4.24.28 bacillolysin
EC 3.4.24.29 aureolysin
EC 3.4.24.30 coccolysin
EC 3.4.24.31 mycolysin
EC 3.4.24.32 β-lytic metalloendopeptidase
EC 3.4.24.33 peptidyl-Asp metalloendopeptidase
EC 3.4.24.34 neutrophil collagenase
EC 3.4.24.35 gelatinase B
EC 3.4.24.36 leishmanolysin
EC 3.4.24.37 saccharolysin
EC 3.4.24.38 gametolysin
EC 3.4.24.39 deuterolysin
EC 3.4.24.40 serralysin
EC 3.4.24.41 atrolysin B
EC 3.4.24.42 atrolysin C
EC 3.4.24.43 atroxase
EC 3.4.24.44 atrolysin E
EC 3.4.24.45 atrolysin F
EC 3.4.24.46 adamalysin
EC 3.4.24.47 horrilysin
EC 3.4.24.48 ruberlysin
EC 3.4.24.49 bothropasin
EC 3.4.24.50 bothrolysin
EC 3.4.24.51 ophiolysin
EC 3.4.24.52 trimerelysin I
EC 3.4.24.53 trimerelysin II
EC 3.4.24.54 mucrolysin
EC 3.4.24.55 pitrilysin
EC 3.4.24.56 insulysin
EC 3.4.24.57 O-sialoglycoprotein endopeptidase
EC 3.4.24.58 russellysin
EC 3.4.24.59 mitochondrial intermediate peptidase
EC 3.4.24.60 dactylysin
EC 3.4.24.61 nardilysin
EC 3.4.24.62 magnolysin
EC 3.4.24.63 meprin B
EC 3.4.24.64 mitochondrial processing peptidase
EC 3.4.24.65 macrophage elastase
EC 3.4.24.66 choriolysin L
EC 3.4.24.67 choriolysin H
EC 3.4.24.68 tentoxilysin
EC 3.4.24.69 bontoxilysin
EC 3.4.24.70 oligopeptidase A
EC 3.4.24.71 endothelin-converting enzyme
EC 3.4.24.72 fibrolase
EC 3.4.24.73 jararhagin
EC 3.4.24.74 fragilysin
EC 3.4.24.75 lysostaphin
EC 3.4.24.76 flavastacin
EC 3.4.24.77 snapalysin
EC 3.4.24.78 gpr endopeptidase
EC 3.4.24.79 pappalysin-1
EC 3.4.24.80 membrane-type matrix metalloproteinase-1
EC 3.4.24.81 ADAM10 endopeptidase
EC 3.4.24.82 ADAMTS-4 endopeptidase
EC 3.4.24.83 anthrax lethal factor endopeptidase
EC 3.4.24.84 Ste24 endopeptidase
EC 3.4.24.85 S2P endopeptidase
EC 3.4.24.86 ADAM 17 endopeptidase
EC 3.4.24.87 ADAMTS13 endopeptidase
EC 3.4.24.88 now EC 3.4.19.15
EC 3.4.24.89 Pro-Pro endopeptidase

EC 3.4.25 Threonine endopeptidases

EC 3.4.25.1 proteasome endopeptidase complex
EC 3.4.25.2 HslU—HslV peptidase

EC 3.4.99 Endopeptidases of unknown catalytic mechanism

EC 3.4.99.1 now EC 3.4.23.28
EC 3.4.99.2 deleted
EC 3.4.99.3 deleted
EC 3.4.99.4 now EC 3.4.23.12
EC 3.4.99.5 now EC 3.4.24.3
EC 3.4.99.6 now EC 3.4.24.21
EC 3.4.99.7 deleted
EC 3.4.99.8 deleted
EC 3.4.99.9 deleted
EC 3.4.99.10 now EC 3.4.24.56 (supplement 3)
EC 3.4.99.11 deleted
EC 3.4.99.12 deleted
EC 3.4.99.13 now EC 3.4.24.32
EC 3.4.99.14 deleted
EC 3.4.99.15 deleted
EC 3.4.99.16 deleted
EC 3.4.99.17 deleted
EC 3.4.99.18 deleted
EC 3.4.99.19 now EC 3.4.23.15
EC 3.4.99.20 deleted
EC 3.4.99.21 deleted
EC 3.4.99.22 now EC 3.4.24.29
EC 3.4.99.23 deleted
EC 3.4.99.24 deleted
EC 3.4.99.25 deleted, included in EC 3.4.23.21
EC 3.4.99.26 now covered by EC 3.4.21.73 and EC 3.4.21.68
EC 3.4.99.27 deleted
EC 3.4.99.28 now EC 3.4.21.60
EC 3.4.99.29 deleted
EC 3.4.99.30 deleted, included in EC 3.4.24.20
EC 3.4.99.31 deleted, included in EC 3.4.24.15
EC 3.4.99.32 now EC 3.4.24.20
EC 3.4.99.33 deleted
EC 3.4.99.34 deleted
EC 3.4.99.35 now EC 3.4.23.36 (supplement 2)
EC 3.4.99.36 now EC 3.4.21.89 (supplement 2)
EC 3.4.99.37 deleted
EC 3.4.99.38 now EC 3.4.23.17
EC 3.4.99.39 deleted
EC 3.4.99.40 deleted
EC 3.4.99.41 now EC 3.4.24.64 (supplement 2)
EC 3.4.99.42 deleted
EC 3.4.99.43 now EC 3.4.23.42 (supplement 6)
EC 3.4.99.44 now EC 3.4.24.55 (supplement 1)
EC 3.4.99.45 now EC 3.4.24.56 (supplement 1)
EC 3.4.99.46 now EC 3.4.25.1 (supplement 6)

EC 3.5 Acting on Carbon-Nitrogen Bonds, other than Peptide Bonds

EC 3.5.1 In Linear Amides

EC 3.5.1.1 asparaginase
EC 3.5.1.2 glutaminase
EC 3.5.1.3 ω-amidase
EC 3.5.1.4 amidase
EC 3.5.1.5 urease
EC 3.5.1.6 β-ureidopropionase
EC 3.5.1.7 ureidosuccinase
EC 3.5.1.8 formylaspartate deformylase
EC 3.5.1.9 arylformamidase
EC 3.5.1.10 formyltetrahydrofolate deformylase
EC 3.5.1.11 penicillin amidase
EC 3.5.1.12 biotinidase
EC 3.5.1.13 aryl-acylamidase
EC 3.5.1.14 N-acyl-aliphatic-L-amino acid amidohydrolase
EC 3.5.1.15 aspartoacylase
EC 3.5.1.16 acetylornithine deacetylase
EC 3.5.1.17 acyl-lysine deacylase
EC 3.5.1.18 succinyl-diaminopimelate desuccinylase
EC 3.5.1.19 nicotinamidase
EC 3.5.1.20 citrullinase
EC 3.5.1.21 N-acetyl-β-alanine deacetylase
EC 3.5.1.22 pantothenase
EC 3.5.1.23 ceramidase
EC 3.5.1.24 choloylglycine hydrolase
EC 3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase
EC 3.5.1.26 N4-(β-N-acetylglucosaminyl)-L-asparaginase
EC 3.5.1.27 deleted, covered by EC 3.5.1.88
EC 3.5.1.28 N-acetylmuramoyl-L-alanine amidase
EC 3.5.1.29 2-(acetamidomethylene)succinate hydrolase
EC 3.5.1.30 5-aminopentanamidase
EC 3.5.1.31 formylmethionine deformylase
EC 3.5.1.32 hippurate hydrolase
EC 3.5.1.33 N-acetylglucosamine deacetylase
EC 3.5.1.34 deleted, same as EC 3.4.13.5
EC 3.5.1.35 D-glutaminase
EC 3.5.1.36 N-methyl-2-oxoglutaramate hydrolase
EC 3.5.1.37 deleted, same as EC 3.5.1.26
EC 3.5.1.38 glutamin-(asparagin-)ase
EC 3.5.1.39 alkylamidase
EC 3.5.1.40 acylagmatine amidase
EC 3.5.1.41 chitin deacetylase
EC 3.5.1.42 nicotinamide-nucleotide amidase
EC 3.5.1.43 peptidyl-glutaminase
EC 3.5.1.44 protein-glutamine glutaminase
EC 3.5.1.45 now EC 6.3.4.6
EC 3.5.1.46 6-aminohexanoate-oligomer exohydrolase
EC 3.5.1.47 N-acetyldiaminopimelate deacetylase
EC 3.5.1.48 acetylspermidine deacetylase
EC 3.5.1.49 formamidase
EC 3.5.1.50 pentanamidase
EC 3.5.1.51 4-acetamidobutyryl-CoA deacetylase
EC 3.5.1.52 peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase
EC 3.5.1.53 N-carbamoylputrescine amidase
EC 3.5.1.54 allophanate hydrolase
EC 3.5.1.55 long-chain-fatty-acyl-glutamate deacylase
EC 3.5.1.56 N,N-dimethylformamidase
EC 3.5.1.57 tryptophanamidase
EC 3.5.1.58 N-benzyloxycarbonylglycine hydrolase
EC 3.5.1.59 N-carbamoylsarcosine amidase
EC 3.5.1.60 N-(long-chain-acyl)ethanolamine deacylase
EC 3.5.1.61 mimosinase
EC 3.5.1.62 acetylputrescine deacetylase
EC 3.5.1.63 4-acetamidobutyrate deacetylase
EC 3.5.1.64 Nα-benzyloxycarbonylleucine hydrolase
EC 3.5.1.65 theanine hydrolase
EC 3.5.1.66 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase
EC 3.5.1.67 4-methyleneglutaminase
EC 3.5.1.68 N-formylglutamate deformylase
EC 3.5.1.69 glycosphingolipid deacylase
EC 3.5.1.70 aculeacin-A deacylase
EC 3.5.1.71 N-feruloylglycine deacylase
EC 3.5.1.72 D-benzoylarginine-4-nitroanilide amidase
EC 3.5.1.73 carnitinamidase
EC 3.5.1.74 chenodeoxycholoyltaurine hydrolase
EC 3.5.1.75 urethanase
EC 3.5.1.76 arylalkyl acylamidase
EC 3.5.1.77 N-carbamoyl-D-amino acid hydrolase
EC 3.5.1.78 glutathionylspermidine amidase
EC 3.5.1.79 phthalyl amidase
EC 3.5.1.80 deleted, identical to EC 3.5.1.25
EC 3.5.1.81 N-acyl-D-amino-acid deacylase
EC 3.5.1.82 N-acyl-D-glutamate deacylase
EC 3.5.1.83 N-acyl-D-aspartate deacylase
EC 3.5.1.84 biuret amidohydrolase
EC 3.5.1.85 (S)-N-acetyl-1-phenylethylamine hydrolase
EC 3.5.1.86 mandelamide amidase
EC 3.5.1.87 N-carbamoyl-L-amino-acid hydrolase
EC 3.5.1.88 peptide deformylase
EC 3.5.1.89 N-acetylglucosaminylphosphatidylinositol deacetylase
EC 3.5.1.90 adenosylcobinamide hydrolase
EC 3.5.1.91 N-substituted formamide deformylase
EC 3.5.1.92 pantetheine hydrolase
EC 3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase
EC 3.5.1.94 γ-glutamyl-γ-aminobutyrate hydrolase
EC 3.5.1.95 N-malonylurea hydrolase
EC 3.5.1.96 succinylglutamate desuccinylase
EC 3.5.1.97 acyl-homoserine-lactone acylase
EC 3.5.1.98 histone deacetylase
EC 3.5.1.99 fatty acid amide hydrolase
EC 3.5.1.100 (R)-amidase
EC 3.5.1.101 L-proline amide hydrolase
EC 3.5.1.102 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
EC 3.5.1.103 N-acetyl-1D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase
EC 3.5.1.104 peptidoglycan-N-acetylglucosamine deacetylase
EC 3.5.1.105 chitin disaccharide deacetylase
EC 3.5.1.106 N-formylmaleamate deformylase
EC 3.5.1.107 maleamate amidohydrolase
EC 3.5.1.108 UDP-3-O-acyl-N-acetylglucosamine deacetylase
EC 3.5.1.109 sphingomyelin deacylase
EC 3.5.1.110 peroxyureidoacrylate/ureidoacrylate amidohydrolase
EC 3.5.1.111 2-oxoglutaramate amidase
EC 3.5.1.112 2'-N-acetylparomamine deacetylase
EC 3.5.1.113 2'''-acetyl-6'''-hydroxyneomycin C deacetylase
EC 3.5.1.114 N-acyl-aromatic-L-amino acid amidohydrolase
EC 3.5.1.115 mycothiol S-conjugate amidase
EC 3.5.1.116 ureidoglycolate amidohydrolase
EC 3.5.1.117 6-aminohexanoate-oligomer endohydrolase
EC 3.5.1.118 γ-glutamyl hercynylcysteine S-oxide hydrolase
EC 3.5.1.119 Pup deamidase
EC 3.5.1.120 transferred, now EC 3.5.99.11
EC 3.5.1.121 protein N-terminal asparagine amidohydrolase
EC 3.5.1.122 protein N-terminal glutamine amidohydrolase
EC 3.5.1.123 γ-glutamylanilide hydrolase
EC 3.5.1.124 protein deglycase
EC 3.5.1.125 N2-acetyl-L-2,4-diaminobutanoate deacetylase
EC 3.5.1.126 oxamate amidohydrolase
EC 3.5.1.127 jasmonoyl-L-amino acid hydrolase
EC 3.5.1.128 deaminated glutathione amidase
EC 3.5.1.129 N5-(cytidine 5′-diphosphoramidyl)-L-glutamine hydrolase
EC 3.5.1.130 [lysine-biosynthesis-protein LysW]-lysine/ornithine hydrolase
EC 3.5.1.131 1-carboxybiuret hydrolase
EC 3.5.1.132 [amino group carrier protein]-ornithine hydrolase
EC 3.5.1.133 Nα-acyl-L-glutamine aminoacylase
EC 3.5.1.134 (indol-3-yl)acetyl-L-aspartate hydrolase

EC 3.5.2 In Cyclic Amides

EC 3.5.2.1 barbiturase
EC 3.5.2.2 dihydropyrimidinase
EC 3.5.2.3 dihydroorotase
EC 3.5.2.4 carboxymethylhydantoinase
EC 3.5.2.5 allantoinase
EC 3.5.2.6 β-lactamase
EC 3.5.2.7 imidazolonepropionase
EC 3.5.2.8 deleted, included in EC 3.5.2.6
EC 3.5.2.9 5-oxoprolinase (ATP-hydrolysing)
EC 3.5.2.10 creatininase
EC 3.5.2.11 L-lysine-lactamase
EC 3.5.2.12 6-aminohexanoate-cyclic-dimer hydrolase
EC 3.5.2.13 2,5-dioxopiperazine hydrolase
EC 3.5.2.14 N-methylhydantoinase (ATP-hydrolysing)
EC 3.5.2.15 cyanuric acid amidohydrolase
EC 3.5.2.16 maleimide hydrolase
EC 3.5.2.17 hydroxyisourate hydrolase
EC 3.5.2.18 enamidase
EC 3.5.2.19 streptothricin hydrolase
EC 3.5.2.20 isatin hydrolase

EC 3.5.3 In Linear Amidines

EC 3.5.3.1 arginase
EC 3.5.3.2 guanidinoacetase
EC 3.5.3.3 creatinase
EC 3.5.3.4 allantoicase
EC 3.5.3.5 formiminoaspartate deiminase
EC 3.5.3.6 arginine deiminase
EC 3.5.3.7 guanidinobutyrase
EC 3.5.3.8 formimidoylglutamase
EC 3.5.3.9 allantoate deiminase
EC 3.5.3.10 D-arginase
EC 3.5.3.11 agmatinase
EC 3.5.3.12 agmatine deiminase
EC 3.5.3.13 formiminoglutamate deiminase
EC 3.5.3.14 amidinoaspartase
EC 3.5.3.15 protein-arginine deiminase
EC 3.5.3.16 methylguanidinase
EC 3.5.3.17 guanidinopropionase
EC 3.5.3.18 dimethylargininase
EC 3.5.3.19 transferred now EC 3.5.1.116
EC 3.5.3.20 diguanidinobutanase
EC 3.5.3.21 methylenediurea deaminase
EC 3.5.3.22 proclavaminate amidinohydrolase
EC 3.5.3.23 N-succinylarginine dihydrolase
EC 3.5.3.24 N1-aminopropylagmatine ureohydrolase
EC 3.5.3.25 Nω-hydroxy-L-arginine amidinohydrolase
EC 3.5.3.26 (S)-ureidoglycine aminohydrolase

EC 3.5.4 In Cyclic Amidines

EC 3.5.4.1 cytosine deaminase
EC 3.5.4.2 adenine deaminase
EC 3.5.4.3 guanine deaminase
EC 3.5.4.4 adenosine deaminase
EC 3.5.4.5 cytidine deaminase
EC 3.5.4.6 AMP deaminase
EC 3.5.4.7 ADP deaminase
EC 3.5.4.8 aminoimidazolase
EC 3.5.4.9 methenyltetrahydrofolate cyclohydrolase
EC 3.5.4.10 IMP cyclohydrolase
EC 3.5.4.11 pterin deaminase
EC 3.5.4.12 dCMP deaminase
EC 3.5.4.13 dCTP deaminase
EC 3.5.4.14 transferred now included in EC 3.5.4.5
EC 3.5.4.15 guanosine deaminase
EC 3.5.4.16 GTP cyclohydrolase I
EC 3.5.4.17 adenosine-phosphate deaminase
EC 3.5.4.18 ATP deaminase
EC 3.5.4.19 phosphoribosyl-AMP cyclohydrolase
EC 3.5.4.20 pyrithiamine deaminase
EC 3.5.4.21 creatinine deaminase
EC 3.5.4.22 1-pyrroline-4-hydroxy-2-carboxylate deaminase
EC 3.5.4.23 blasticidin-S deaminase
EC 3.5.4.24 sepiapterin deaminase
EC 3.5.4.25 GTP cyclohydrolase II
EC 3.5.4.26 diaminohydroxyphosphoribosylaminopyrimidine deaminase
EC 3.5.4.27 methenyltetrahydromethanopterin cyclohydrolase
EC 3.5.4.28 S-adenosylhomocysteine deaminase
EC 3.5.4.29 GTP cyclohydrolase IIa
EC 3.5.4.30 dCTP deaminase (dUMP-forming)
EC 3.5.4.31 S-methyl-5'-thioadenosine deaminase
EC 3.5.4.32 8-oxoguanine deaminase
EC 3.5.4.33 tRNA(adenine34) deaminase
EC 3.5.4.34 tRNAAla(adenine37) deaminase
EC 3.5.4.35 tRNA(cytosine8) deaminase
EC 3.5.4.36 mRNA(cytosine6666) deaminase
EC 3.5.4.37 double-stranded RNA adenine deaminase
EC 3.5.4.38 single-stranded DNA cytosine deaminase
EC 3.5.4.39 GTP cyclohydrolase IV
EC 3.5.4.40 aminodeoxyfutalosine deaminase
EC 3.5.4.41 5'-deoxyadenosine deaminase
EC 3.5.4.42 N-isopropylammelide isopropylaminohydrolase
EC 3.5.4.43 hydroxydechloroatrazine ethylaminohydrolase
EC 3.5.4.44 ectoine hydrolase
EC 3.5.4.45 melamine deaminase
EC 3.5.4.46 cAMP deaminase

EC 3.5.5 In Nitriles

EC 3.5.5.1 nitrilase
EC 3.5.5.2 ricinine nitrilase
EC 3.5.5.3 now EC 4.3.99.1
EC 3.5.5.4 cyanoalanine nitrilase
EC 3.5.5.5 arylacetonitrilase
EC 3.5.5.6 bromoxynil nitrilase
EC 3.5.5.7 aliphatic nitrilase
EC 3.5.5.8 thiocyanate hydrolase

EC 3.5.99 In Other Compounds

EC 3.5.99.1 riboflavinase
EC 3.5.99.2 aminopyrimidine aminohydrolase
EC 3.5.99.3 transferred now EC 3.5.4.43
EC 3.5.99.4 transferred, now EC 3.5.4.42
EC 3.5.99.5 2-aminomuconate deaminase
EC 3.5.99.6 glucosamine-6-phosphate deaminase
EC 3.5.99.7 1-aminocyclopropane-1-carboxylate deaminase
EC 3.5.99.8 5-nitroanthranilic acid aminohydrolase
EC 3.5.99.9 2-nitroimidazole nitrohydrolase
EC 3.5.99.10 2-iminobutanoate/2-iminopropanoate deaminase
EC 3.5.99.11 2-aminomuconate deaminase (2-hydroxymuconate-forming)

EC 3.6 Acting on Acid Anhydrides

EC 3.6.1 In Phosphorus-Containing Anhydrides

EC 3.6.1.1 inorganic diphosphatase
EC 3.6.1.2 trimetaphosphatase
EC 3.6.1.3 adenosinetriphosphatase
EC 3.6.1.4 deleted, included in EC 3.6.1.3
EC 3.6.1.5 apyrase
EC 3.6.1.6 nucleoside diphosphate phosphatase
EC 3.6.1.7 acylphosphatase
EC 3.6.1.8 ATP diphosphatase
EC 3.6.1.9 nucleotide diphosphatase
EC 3.6.1.10 endopolyphosphatase
EC 3.6.1.11 exopolyphosphatase
EC 3.6.1.12 dCTP diphosphatase
EC 3.6.1.13 ADP-ribose diphosphatase
EC 3.6.1.14 adenosine-tetraphosphatase
EC 3.6.1.15 nucleoside-triphosphate phosphatase
EC 3.6.1.16 CDP-glycerol diphosphatase
EC 3.6.1.17 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
EC 3.6.1.18 FAD diphosphatase
EC 3.6.1.19 transferred, now included in EC 3.6.1.9
EC 3.6.1.20 5'-acylphosphoadenosine hydrolase
EC 3.6.1.21 ADP-sugar diphosphatase
EC 3.6.1.22 NAD+ diphosphatase
EC 3.6.1.23 dUTP diphosphatase
EC 3.6.1.24 nucleoside phosphoacylhydrolase
EC 3.6.1.25 triphosphatase
EC 3.6.1.26 CDP-diacylglycerol diphosphatase
EC 3.6.1.27 undecaprenyl-diphosphate phosphatase
EC 3.6.1.28 thiamine-triphosphatase
EC 3.6.1.29 bis(5'-adenosyl)-triphosphatase
EC 3.6.1.30 m7G(5')pppN diphosphatase
EC 3.6.1.31 deleted now covered by EC 3.6.1.59 and EC 3.6.1.62.
EC 3.6.1.32 now EC 3.6.4.1
EC 3.6.1.33 now EC 3.6.4.2
EC 3.6.1.34 now EC 3.6.3.14
EC 3.6.1.35 now EC 3.6.3.6
EC 3.6.1.36 now EC 3.6.3.10
EC 3.6.1.37 now EC 3.6.3.9
EC 3.6.1.38 now EC 3.6.3.8
EC 3.6.1.39 thymidine-triphosphatase
EC 3.6.1.40 guanosine-5'-triphosphate,3'-diphosphate phosphatase
EC 3.6.1.41 bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
EC 3.6.1.42 guanosine-diphosphatase
EC 3.6.1.43 dolichyldiphosphatase
EC 3.6.1.44 oligosaccharide-diphosphodolichol diphosphatase
EC 3.6.1.45 UDP-sugar diphosphatase
EC 3.6.1.46 now EC 3.6.5.1
EC 3.6.1.47 now EC 3.6.5.2
EC 3.6.1.48 now EC 3.6.5.3
EC 3.6.1.49 now EC 3.6.5.4
EC 3.6.1.50 now EC 3.6.5.5
EC 3.6.1.51 now EC 3.6.5.6
EC 3.6.1.52 diphosphoinositol-polyphosphate diphosphatase
EC 3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
EC 3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase
EC 3.6.1.55 8-oxo-dGTP diphosphatase
EC 3.6.1.56 2-hydroxy-dATP diphosphatase
EC 3.6.1.57 UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase
EC 3.6.1.58 8-oxo-dGDP phosphatase
EC 3.6.1.59 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase
EC 3.6.1.60 diadenosine hexaphosphate hydrolase (AMP-forming)
EC 3.6.1.61 diadenosine hexaphosphate hydrolase (ATP-forming)
EC 3.6.1.62 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase
EC 3.6.1.63 α-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
EC 3.6.1.64 inosine diphosphate phosphatase
EC 3.6.1.65 (d)CTP diphosphatase
EC 3.6.1.66 XTP/dITP diphosphatase
EC 3.6.1.67 dihydroneopterin triphosphate diphosphatase
EC 3.6.1.68 geranyl diphosphate phosphohydrolase
EC 3.6.1.69 8-oxo-(d)GTP phosphatase
EC 3.6.1.70 guanosine-5'-diphospho-5'-[DNA] diphosphatase
EC 3.6.1.71 adenosine-5'-diphospho-5'-[DNA] diphosphatase
EC 3.6.1.72 DNA-3'-diphospho-5'-guanosine diphosphatase
EC 3.6.1.73 inosine/xanthosine triphosphatase

EC 3.6.2 In Sulfonyl-Containing Anhydrides

EC 3.6.2.1 adenylylsulfatase
EC 3.6.2.2 phosphoadenylylsulfatase

EC 3.6.3 Acting on acid anhydrides; catalysing transmembrane movement of substances

EC 3.6.3.1 now EC 7.6.2.1
EC 3.6.3.2 now EC 7.2.2.14
EC 3.6.3.3 now EC 7.2.2.21
EC 3.6.3.4 now EC 7.2.2.9
EC 3.6.3.5 now EC 7.2.2.12
EC 3.6.3.6 now EC 7.1.2.1
EC 3.6.3.7 now EC 7.2.2.3
EC 3.6.3.8 now EC 7.2.2.10
EC 3.6.3.9 now EC 7.2.2.13
EC 3.6.3.10 now EC 7.2.2.19
EC 3.6.3.11 Cl--transporting ATPase
EC 3.6.3.12 now EC 7.2.2.6
EC 3.6.3.13 deleted, identical to EC 3.6.3.1
EC 3.6.3.14 now EC 7.1.2.2
EC 3.6.3.15 now EC 7.2.2.1
EC 3.6.3.16 transferred now EC 7.3.2.7
EC 3.6.3.17 transferred now various members of sub-subclass EC 7.5.2
EC 3.6.3.18 now EC 7.5.2.2
EC 3.6.3.19 now EC 7.5.2.1
EC 3.6.3.20 now EC 7.6.2.10
EC 3.6.3.21 now EC 7.4.2.1
EC 3.6.3.22 now EC 7.4.2.2
EC 3.6.3.23 now EC 7.4.2.6
EC 3.6.3.24 now EC 7.2.2.11
EC 3.6.3.25 now EC 7.3.2.3
EC 3.6.3.26 now EC 7.3.2.4
EC 3.6.3.27 now EC 7.3.2.1
EC 3.6.3.28 now EC 7.3.2.2
EC 3.6.3.29 now EC 7.3.2.5
EC 3.6.3.30 now EC 7.3.2.7
EC 3.6.3.31 now EC 7.3.2.11
EC 3.6.3.32 now EC 7.3.2.9
EC 3.6.3.33 now EC 7.3.2.8
EC 3.6.3.34 now EC 7.3.2.16, EC 7.3.2.17 and EC 7.3.2.18
EC 3.6.3.35 now EC 7.3.2.5
EC 3.6.3.36 now EC 7.6.2.7
EC 3.6.3.37 now EC 7.6.2.6
EC 3.6.3.38 now EC 7.6.2.12
EC 3.6.3.39 lipopolysaccharide-transporting ATPase
EC 3.6.3.40 tnow EC 7.5.2.4
EC 3.6.3.41 now EC 7.6.2.5
EC 3.6.3.42 now EC 7.5.2.3
EC 3.6.3.43 now EC 7.4.2.5
EC 3.6.3.44 now EC 7.6.2.2
EC 3.6.3.45 included with EC 7.6.2.2
EC 3.6.3.46 now EC 7.2.2.2
EC 3.6.3.47 now EC 7.6.2.4
EC 3.6.3.48 now EC 7.4.2.7
EC 3.6.3.49 now EC 5.6.1.6
EC 3.6.3.50 now EC 7.4.2.8
EC 3.6.3.51 now EC 7.4.2.3
EC 3.6.3.52 now EC 7.4.2.4
EC 3.6.3.53 now EC 7.2.2.15
EC 3.6.3.54 now EC 7.2.2.8
EC 3.6.3.55 now EC 7.3.2.6

EC 3.6.4 Acting on acid anhydrides; involved in cellular and subcellular movement

EC 3.6.4.1 now EC 5.6.1.8
EC 3.6.4.2 now EC 5.6.1.2
EC 3.6.4.3 now EC 5.6.1.1
EC 3.6.4.4 now EC 5.6.1.3
EC 3.6.4.5 now EC 5.6.1.4
EC 3.6.4.6 vesicle-fusing ATPase
EC 3.6.4.7 peroxisome-assembly ATPase
EC 3.6.4.8 now EC 5.6.1.5
EC 3.6.4.9 now EC 5.6.1.7
EC 3.6.4.10 non-chaperonin molecular chaperone ATPase
EC 3.6.4.11 deleted
EC 3.6.4.12 DNA helicase
EC 3.6.4.13 RNA helicase

EC 3.6.5 Acting on GTP; involved in cellular and subcellular movement

EC 3.6.5.1 heterotrimeric G-protein GTPase
EC 3.6.5.2 small monomeric GTPase
EC 3.6.5.3 protein-synthesizing GTPase
EC 3.6.5.4 signal-recognition-particle GTPase
EC 3.6.5.5 dynamin GTPase
EC 3.6.5.6 tubulin GTPase

EC 3.7 Acting on Carbon-Carbon Bonds

EC 3.7.1 In Ketonic Substances

EC 3.7.1.1 oxaloacetase
EC 3.7.1.2 fumarylacetoacetase
EC 3.7.1.3 kynureninase
EC 3.7.1.4 phloretin hydrolase
EC 3.7.1.5 acylpyruvate hydrolase
EC 3.7.1.6 acetylpyruvate hydrolase
EC 3.7.1.7 β-diketone hydrolase
EC 3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
EC 3.7.1.9 2-hydroxymuconate-semialdehyde hydrolase
EC 3.7.1.10 cyclohexane-1,3-dione hydrolase
EC 3.7.1.11 cyclohexane-1,2-dione hydrolase
EC 3.7.1.12 cobalt-precorrin 5A hydrolase
EC 3.7.1.13 2-hydroxy-6-oxo-6-(2'-aminobiphenyl)hexa-2,4-dienoate hydrolase
EC 3.7.1.14 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase
EC 3.7.1.15 transferred now EC 4.2.1.138
EC 3.7.1.16 transferred now EC 3.3.2.12
EC 3.7.1.17 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
EC 3.7.1.18 6-oxocamphor hydrolase
EC 3.7.1.19 2,6-dihydroxypseudooxynicotine hydrolase
EC 3.7.1.20 3-fumarylpyruvate hydrolase
EC 3.7.1.21 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase
EC 3.7.1.22 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing)
EC 3.7.1.23 maleylpyruvate hydrolase
EC 3.7.1.24 2,4-diacetylphloroglucinol hydrolase
EC 3.7.1.25 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase
EC 3.7.1.26 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase

EC 3.8 Acting on Halide Bonds

EC 3.8.1 In C-Halide Compounds

EC 3.8.1.1 alkylhalidase
EC 3.8.1.2 (S)-2-haloacid dehalogenase
EC 3.8.1.3 haloacetate dehalogenase
EC 3.8.1.4 now EC 1.97.1.10
EC 3.8.1.5 haloalkane dehalogenase
EC 3.8.1.6 4-chlorobenzoate dehalogenase
EC 3.8.1.7 4-chlorobenzoyl-CoA dehalogenase
EC 3.8.1.8 atrazine chlorohydrolase
EC 3.8.1.9 (R)-2-haloacid dehalogenase
EC 3.8.1.10 2-haloacid dehalogenase (configuration-inverting)
EC 3.8.1.11 2-haloacid dehalogenase (configuration-retaining)

EC 3.8.2 In P-Halide Compounds

EC 3.8.2.1 now EC 3.1.8.2

EC 3.9 Acting on Phosphorus-Nitrogen Bonds

EC 3.9.1.1 phosphoamidase
EC 3.9.1.2 protein arginine phosphatase
EC 3.9.1.3 phosphohistidine phosphatase

EC 3.10 Acting on Sulfur-Nitrogen Bonds

EC 3.10.1.1 N-sulfoglucosamine sulfohydrolase
EC 3.10.1.2 cyclamate sulfohydrolase

EC 3.11 Acting on Carbon-Phosphorus Bonds

EC 3.11.1.1 phosphonoacetaldehyde hydrolase
EC 3.11.1.2 phosphonoacetate hydrolase
EC 3.11.1.3 phosphonopyruvate hydrolase

EC 3.12 Acting on Sulfur-Sulfur Bonds

EC 3.12.1.1 trithionate hydrolase

EC 3.13 Acting on Carbon-Sulfur Bonds

EC 3.13.1.1 UDP-sulfoquinovose synthase
EC 3.13.1.2 deleted probably EC 4.4.1.21
EC 3.13.1.3 2'-hydroxybiphenyl-2-sulfinate desulfinase
EC 3.13.1.4 3-sulfinopropanoyl-CoA desulfinase
EC 3.13.1.5 carbon disulfide hydrolase
EC 3.13.1.6 [CysO sulfur-carrier protein]-S-L-cysteine hydrolase
EC 3.13.1.7 carbonyl sulfide hydrolase
EC 3.13.1.8 S-adenosyl-L-methionine hydrolase (adenosine-forming)
EC 3.13.1.9 S-inosyl-L-homocysteine hydrolase