kallikrein-1 Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykini…

https://www.uniprot.org/uniprot/P29590 Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA dam…

https://www.uniprot.org/uniprot/P20396 As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as m…

https://www.uniprot.org/uniprot/P41159Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in t…

- https://www.uniprot.org/uniprot/Q15848 Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation a…

Alpha-2A adrenergic receptor Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonid…

https://www.uniprot.org/uniprot/P50552 Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, pl…

CS MALLTAAARL LGTKNASCLV LAARHAS PDH MRKMLAAVSR VLSGASQKPA SRVLVASRN Fumarate hydratase MYRALRLLAR SRPLVRAPAA ALASAPGLGG AAVPSFWPPN AARM Long-chain specific acyl-CoA dehydrogenase MAARLLRGSL RVLGGHRAPR QLPAARCSHS Pyruvate carboxylase MLKFR…

https://www.uniprot.org/uniprot/P25116 活性化されたトロンビンと高い親和性で結合し、Gq経由でホスホイノシチドを加水分解する。血小板の活性化と血管の発達に働く。 High affinity receptor for activated thrombin coupled to G proteins that stimulat…