EC 7. Translocases

EC 7.1 Catalysing the translocation of hydrons（水素イオンを移動させる）

EC 7.1.1 Hydron translocation or charge separation linked to oxidoreductase reactions（酸化還元反応を伴う）
  • EC 7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
  • EC 7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
  • EC 7.1.1.3 ubiquinol oxidase (H+-transporting)
  • EC 7.1.1.4 caldariellaquinol oxidase (H+-transporting)
  • EC 7.1.1.5 menaquinol oxidase (H+-transporting)
  • EC 7.1.1.6 plastoquinol—plastocyanin reductase
  • EC 7.1.1.7 quinol oxidase (electrogenic, proton-motive force generating)
  • EC 7.1.1.8 quinol—cytochrome-c reductase
  • EC 7.1.1.9 cytochrome-c oxidase
EC 7.1.2 Hydron translocation linked to the hydrolysis of a nucleoside triphosphate（ATP加水分解を伴う）
  • EC 7.1.2.1 H+-exporting ATPase
  • EC 7.1.2.2 H+-transporting two-sector ATPase
EC 7.1.3 Hydron translocation linked to the hydrolysis of diphosphate（ピロリン酸の加水分解を伴う）
  • EC 7.1.3.1 H+-exporting diphosphatase

EC 7.2 Catalysing the translocation of inorganic cations（無機陽イオンの移動を伴う）

EC 7.2.1 Linked to oxidoreductase reactions（酸化還元反応を伴う）
  • EC 7.2.1.1 NADH:ubiquinone reductase (Na+-transporting)
  • EC 7.2.1.2 ferredoxin—NAD+ oxidoreductase (Na+-transporting)
  • EC 7.2.1.3 ascorbate ferrireductase (transmembrane)
EC 7.2.2 Linked to the hydrolysis of a nucleoside triphosphate（ヌクレオシド三リン酸の加水分解を伴う）
  • EC 7.2.2.1 Na+-transporting two-sector ATPase
  • EC 7.2.2.2 ABC-type Cd2+ transporter
  • EC 7.2.2.3 P-type Na+ transporter
  • EC 7.2.2.4 ABC-type Na+ transporter
  • EC 7.2.2.5 ABC-type Mn2+ transporter
  • EC 7.2.2.6 P-type K+ transporter
  • EC 7.2.2.7 ABC-type Fe3+ transporter
  • EC 7.2.2.8 P-type Cu+ transporter
  • EC 7.2.2.9 P-type Cu2+ transporter
  • EC 7.2.2.10 P-type Ca2+ transporter
  • EC 7.2.2.11 ABC-type Ni2+ transporter
  • EC 7.2.2.12 P-type Zn2+ transporter
  • EC 7.2.2.13 Na+/K+-exchanging ATPase
  • EC 7.2.2.14 P-type Mg2+ transporter
  • EC 7.2.2.15 P-type Ag+ transporter
  • EC 7.2.2.16 ABC-type ferric hydroxamate transporter
  • EC 7.2.2.17 ABC-type ferric enterobactin transporter
  • EC 7.2.2.18 ABC-type ferric citrate transporter
  • EC 7.2.2.19 H+/K+-exchanging ATPase
  • EC 7.2.2.20 ABC-type Zn2+ transporter
  • EC 7.2.2.21 Cd2+-exporting ATPase
EC 7.2.4 Linked to decarboxylation（脱炭酸反応）
  • EC 7.2.4.1 carboxybiotin decarboxylase
  • EC 7.2.4.2 oxaloacetate decarboxylase (Na+ extruding)
  • EC 7.2.4.3 (S)-methylmalonyl-CoA decarboxylase (sodium-transporting)
  • EC 7.2.4.4 biotin-dependent malonate decarboxylase
  • EC 7.2.4.5 glutaconyl-CoA decarboxylase

EC 7.3 Catalysing the translocation of inorganic anions and their chelates（無機陰イオンが移動する）

EC 7.3.2 Linked to the hydrolysis of a nucleoside triphosphate
  • EC 7.3.2.1 ABC-type phosphate transporter
  • EC 7.3.2.2 ABC-type phosphonate transporter
  • EC 7.3.2.3 ABC-type sulfate transporter
  • EC 7.3.2.4 ABC-type nitrate transporter
  • EC 7.3.2.5 ABC-type molybdate transporter
  • EC 7.3.2.6 ABC-type tungstate transporter
  • EC 7.3.2.7 arsenite-transporting ATPase

EC 7.4 Catalysing the translocation of amino acids and peptides

EC 7.4.2 Linked to the hydrolysis of a nucleoside triphosphate
  • EC 7.4.2.1 ABC-type polar-amino-acid transporter
  • EC 7.4.2.2 ABC-type nonpolar-amino-acid transporter
  • EC 7.4.2.3 mitochondrial protein-transporting ATPase
  • EC 7.4.2.4 chloroplast protein-transporting ATPase
  • EC 7.4.2.5 bacterial ABC-type protein transporter
  • EC 7.4.2.6 ABC-type oligopeptide transporter
  • EC 7.4.2.7 ABC-type α-factor-pheromone transporter
  • EC 7.4.2.8 protein-secreting ATPase
  • EC 7.4.2.9 ABC-type dipeptide transporter
  • EC 7.4.2.10 ABC-type glutathione transporter
  • EC 7.4.2.11 ABC-type methionine transporter
  • EC 7.4.2.12 ABC-type cystine transporter
  • EC 7.4.2.13 ABC-type tyrosine transporter

EC 7.5 Catalysing the translocation of carbohydrates and their derivatives

EC 7.5.2 Linked to the hydrolysis of a nucleoside triphosphate
  • EC 7.5.2.1 ABC-type maltose transporter
  • EC 7.5.2.2 ABC-type oligosaccharide transporter
  • EC 7.5.2.3 ABC-type β-glucan transporter
  • EC 7.5.2.4 ABC-type teichoic-acid transporter
  • EC 7.5.2.5 ABC-type lipopolysaccharide transporter
  • EC 7.5.2.6 ABC-type lipid A-core oligosaccharide transporter
  • EC 7.5.2.7 ABC-type D-ribose transporter
  • EC 7.5.2.8 ABC-type D-allose transporter
  • EC 7.5.2.9 ABC-type D-galactofuranose transporter
  • EC 7.5.2.10 ABC-type D-xylose transporter
  • EC 7.5.2.11 ABC-type D-galactose transporter
  • EC 7.5.2.12 ABC-type L-arabinose transporter
  • EC 7.5.2.13 ABC-type D-xylose/L-arabinose transporter

EC 7.6 Catalysing the translocation of other compounds

EC 7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
  • EC 7.6.2.1 P-type phospholipid transporter
  • EC 7.6.2.2 ABC-type xenobiotic transporter
  • EC 7.6.2.3 ABC-type glutathione-S-conjugate transporter
  • EC 7.6.2.4 ABC-type fatty-acyl-CoA transporter
  • EC 7.6.2.5 ABC-type heme transporter
  • EC 7.6.2.6 ABC-type guanine transporter
  • EC 7.6.2.7 ABC-type taurine transporter
  • EC 7.6.2.8 ABC-type vitamin B12 transporter
  • EC 7.6.2.9 ABC-type quaternary amine transporter
  • EC 7.6.2.10 ABC-type glycerol 3-phosphate transporter
  • EC 7.6.2.11 ABC-type polyamine transporter
  • EC 7.6.2.12 ABC-type capsular-polysaccharide transporter
  • EC 7.6.2.13 ABC-type autoinducer-2 transporter
  • EC 7.6.2.14 ABC-type aliphatic sulfonate transporter
  • EC 7.6.2.15 ABC-type thiamine transporter
  • EC 7.6.2.16 ABC-type putrescine transporter

ABCトランスポーター

多剤耐性に関わるP糖タンパク質がその一例である。
イオン、糖、アミノ酸、その他の極性分子、非極性分しを輸送する。
２つのヌクレオチド結合ドメインが細胞質側、残る２つのドメインは６つの膜貫通ヘリックスからなる膜貫通ドメイン、合計４つのドメインをもつ。