2021-10-01から1ヶ月間の記事一覧

ATP synthase

ATP synthase F1 subunit beta https://www.uniprot.org/uniprot/P06576 Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by e…

AMPKの活性化

Thr-172のリン酸化による活性化。 LKB1(Liver Kinase B1) CaMKK2 (Calcium/calmodulin-dependent protein kinase kinase 2) によるリン酸化を受ける。 LKB1、CaMKK2はともにPKAによるリン酸化を受けて活性化される。

血液凝固因子

Coagulation factor VII https://www.uniprot.org/uniprot/P08709 Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor…

ジペプチジルペプチダーゼ dipeptidyl peptidase

N-末端から2アミノ酸を遊離させる。 細胞質に局在するもの、膜結合型、分泌されるものなど Dipeptidyl peptidase 1 https://www.uniprot.org/uniprot/P53634 Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide…

PGE2受容体

Prostaglandin E2 receptor EP1 subtype https://www.uniprot.org/uniprot/P34995 Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger sy…

プロスタグランジン輸送

Prostaglandin transporter https://www.uniprot.org/uniprot/Q92959 Solute carrier organic anion transporter family member 2A1 Transports PGD2, as well as PGE1, PGE2 and PGF2A. Mediates the clearance of prostaglandins from the circulation thr…

ホスホリパーゼA2

Cytosolic phospholipase A2 https://www.uniprot.org/uniprot/P47712Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the infl…