ATP synthase F1 subunit beta https://www.uniprot.org/uniprot/P06576 Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by e…

Thr-172のリン酸化による活性化。 LKB1（Liver Kinase B1） CaMKK2 (Calcium/calmodulin-dependent protein kinase kinase 2) によるリン酸化を受ける。 LKB1、CaMKK2はともにPKAによるリン酸化を受けて活性化される。

Coagulation factor VII https://www.uniprot.org/uniprot/P08709 Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor…

N-末端から２アミノ酸を遊離させる。 細胞質に局在するもの、膜結合型、分泌されるものなど Dipeptidyl peptidase 1 https://www.uniprot.org/uniprot/P53634 Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide…

Prostaglandin E2 receptor EP1 subtype https://www.uniprot.org/uniprot/P34995 Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger sy…

Prostaglandin transporter https://www.uniprot.org/uniprot/Q92959 Solute carrier organic anion transporter family member 2A1 Transports PGD2, as well as PGE1, PGE2 and PGF2A. Mediates the clearance of prostaglandins from the circulation thr…

Cytosolic phospholipase A2 https://www.uniprot.org/uniprot/P47712Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the infl…

Angiotensinogen https://www.uniprot.org/uniprot/P01019 Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth…

ghrelin Growth hormone secretagogue Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulate…

Vasopressin V2 receptor Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption. https://www.uniprot.org/uniprot/P30518 Vasopressin V…

ATP-sensitive inward rectifier potassium channel 11 IKATP This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it…

Platelet glycoprotein Ib alpha chain 血小板の表面にあり、VWFのA1ドメインと結合して血小板血栓形成に働く。 GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, wh…

骨組織は、破骨細胞による吸収除去と骨芽細胞による新生骨の形成（リモデリング）により作られる。 破骨細胞の前駆細胞はRANK（受容体）をもち、リガンド（RANKL）の結合により成熟する。 https://seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2019.910529/dat…

https://www.uniprot.org/uniprot/P35558 Cytosolic phosphoenolpyruvate carboxykinase that catalyzes the reversible decarboxylation and phosphorylation of oxaloacetate (OAA) and acts as the rate-limiting enzyme in gluconeogenesis (PubMed:3019…

イオンチャネル型 AMPA受容体 カイニン酸受容体 NMDA受容体 代謝型グルタミン酸受容体 グループⅠ グループⅡ グループⅢ